Jo L. Freudenheim
PhD
Associate Dean for Faculty Affairs
Deputy Director
SUNY Distinguished Professor
Research Topics/Projects
Cancer epidemiology, using epidemiologic tools to understand carcinogenesis at the population, individual, tissue and molecular levels to better prevent and control the disease risk and progression. Much of my work includes a focus on nutrition and alcohol. . Recent projects include examination of factors associated with mortality after a breast cancer diagnosis, a study of the breast microbiome and a study of DNA methylation in lung tissues from smokers, non-smokers and electronic cigarette users.
Selected Publications
- *Koyratty BNS, McCann SE, Millen A, Nie J, Trevisan M, Freudenheim JL. Sugar-sweetened soda consumption and total and breast cancer mortality: The Western New York Exposures and Breast Cancer (WEB) Study. Ca Epidemiol Biomarkers Prev 2021;30:945-52. (Included in AACR annual report on cancer to the U.S. Congress.)
- Mattick LJ, Nazario CM, Rosario-Rosado RV, Schelske-Santos M, Mansilla-Rivera I, Ramirez-Marrero FA, Nie J, Freudenheim JL. Perinatal factors, female breast cancer, and associated risk factors in Puerto Rico: Evidence from the Atabey Epidemiology of breast cancer study. Cancer Epidemiol Biomarkers Prev 2022;33:373-379.
- Ramírez-Marrero FA, Nazario CM, Rosario-Rosado RV, Schelske-Santos M, Mansilla-Rivera I, Nie J, Hernández-Santiago J, Freudenheim JL. Anthropometric measures and breast cancer risk among Hispanic women in Puerto Rico. Ca Causes Control 2022;33:971-81.
- Nazario CM, Rosario-Rosado RV, Piovanetti P, Nie J, Hernández-Santiago J, Schelske-Santos M, Mansilla I, Ramírez-Marrero F, Venegas H, Freudenheim JL. Sun exposure is associated with a reduced breast cancer risk among women living in the Caribbean: The Atabey study in Puerto Rico. Cancer Epidemiol Biomarkers Prev 2022;31:430-435.
- Pearlman R, Frankel WL, Swanson BJ, Jones D, Zhao W, Yilmaz A, Miller K, Bacher J, Bigley C, Nelsen L, Goodfellow PJ, Goldberg RM, Paskett E, Shields PG, Freudenheim JL, Stanich PP, Lattimer I, Arnold M, Prior TW, Haut M, Kalady MF, Heald B, Paquette I, Draper DJ, Brell JM, Mahesh S, Weeman K, Bastola S, Zangmeister J, Gowda A, Kencana F, Malcolm A, Lui Y, Cole S, Bane C, Li C, Rehmus E, Pritchard CC, Shirts BH, Jacobsen A, Cummings SA, de la Chapelle A, Hampel H on behalf of the Ohio Colorectal Prevention Initiative Study Group. Prospective statewide study of universal screening for hereditary colorectal cancer: The Ohio Colorectal Cancer Prevention Initiative Study. JCO Precision Oncology 2021;5:PO.20.00525.
- Mongiovi JM, Freudenheim JL, Moysich KB, McCann SE. Glycemic index, glycemic load and risk of ovarian cancer in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cohort. J Nutr 2021;151:1597-1608.
- Freudenheim JL. Alcohol's effects on breast cancer in women. Alcohol Research (invited review) 2020;40(2):11. doi.org/10.35946/arcr.v40.2.11.
- Tsai M, Song M-A, McAndrew C, Brasky TM, Freudenheim JL, Mathé E, McElroy J, Reisinger SA, Shields PG, Wewers MD. Electronic vs. combustible cigarette effects on inflammasome component release into human lung. Am J Respir Crit Care Med 2019;199:922-25. PMID: 30608866.
- DiVita MA, Granger CV, Goldstein R, Niewczyk PM, Freudenheim JL. Mandated quality of care metrics for Medicare patients: Examining new or worsened pressure ulcers and rehabilitation outcomes in United States inpatient rehabilitation facilities. Arch Phys Med Rehab 2018;99:1514-24. PMID: 29649450.
- Pearlman R, Frankel WL, Swanson B, Zhao W, Yilmaz A, Miller K, Bacher J, Bigley C, Nelsen L, Goodfellow PJ, Goldberg RM, Paskett E, Shields PG, Freudenheim JL, Stanich PP, Lattimer I, Arnold M, Liyanarachchi S, Kalady M, Heald B, Greenwood C, Paquette I, Prues M, Draper DJ, Lindeman C, Kuebler JP, Reynolds K, Brell JM, Shaper AA, Mahesh S, Buie N, Weeman K, Shine K, Haut M, Edwards J, Bastola S, Wickham K, Khanduja KS, Zacks R, Pritchard CC, Shirts BH, Jacobson A, Allen B, de la Chapelle A, Hampel H; Ohio Colorectal Cancer Prevention Initiative Study Group. Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer. JAMA Oncol. 2017 Apr 1;3(4):464-471. doi: 10.1001/jamaoncol.2016.5194. PMID: 27978560.
- Freudenheim JL, Genco RJ, LaMonte MJ, Millen AE, Hovey KM, Mai X, Nwizu N, Andrews CA, Wactawski-Wende J. Periodontal disease and breast cancer: Prospective cohort study of postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2016;25(1): 43-50. PMID: 26689418.
- Weaver AM, McCann SE, Nie J, Edge SB, Nochajski TH, Russell M, Trevisan M, Freudenheim JL. Alcohol intake over the life course and breast cancer survival in Western New York Exposures and Breast Cancer (WEB) Study: Quantity and Intensity of Intake. Br Ca Res Treat. 2013;139:245-53. PMID: 23605086.
- Tao MH, Shields PG, Nie J, Marian C, McCann SE, Millen A, Ambrosone C, Hutson A, Edge SB, Krishnan SS, Xie B, Winston J, Vito D, Russell M, Nochajski T, Trevisan M, Freudenheim JL. Alcohol consumption in relation to aberrant DNA methylation in breast tumors. Alcohol. 2011;45:689-699. PMID: 21168302.
- Freudenheim JL, Ambrosone CB, Moysich KB, Vena JE, Graham S, Marshall JR, Muti P, Laughlin R, Nemoto T, Harty LC, Crits GA, Chan AWK, Shields P. Alcohol dehydrogenase 3 genotype modification of the association of alcohol consumption with breast cancer. Cancer Causes Control. 1999;10:369-7. PMID: 10530606.
- Ambrosone CB, Freudenheim JL, Graham S, Marshall JR, Vena JE, Brasure JR, Michalek AM, Laughlin R, Nemoto T, Gillenwater KA, Harrington AM, Sheilds PG. Cigarette smoking, N-acetyltransferase genetic polymorphisms and breast cancer risk. JAMA. 1996;276:1494-501. PMID: 8903261.
- Freudenheim JL, Marshall JR, Vena JE, Laughlin R, Brasure JR, Swanson MK, Nemoto T, Graham S. Premenopausal breast cancer risk and intake of vegetables, fruits and related nutrients. J Natl Cancer Inst. 1996;88:340-348. PMID: 8609642.
- Freudenheim JL, Marshall, JR, Graham S, Hellmann R, Vena JE, Bandera E, Muti P, Swanson M, Nemoto T. Exposure to breast milk in infancy and the risk of breast cancer. Epidemiol. 1994;5:324-31. PMID: 8038247.
- Freudenheim JL, Graham S, Marshall JR, Haughey BP, Cholewinski S, Wilkinson G. Folate intake and carcinogenesis of the colon and rectum. Int J Epidemiol 1991;20:368-74. PMID: 1917236.