Assessing the health risks and biomarkers of exposure; effect and susceptibility to pesticides, air pollutants and persistent halogenated aromatic hydrocarbons.
Gao L, Mutlu E, Collins LB, Walker NJ, Hartwell HJ, Olson JR, Sun W, Gold A, Ball LM, Swenberg JA. DNA Product Formation in Female Sprague-Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure. Chem Res Toxicol. (2017) Mar 20;30(3):794-803. doi: 10.1021/acs.chemrestox.6b00368. Epub 2017 Feb 16
Ismail AA, Bonner MR, Hendy O, Rasoul GA, Wang L, Olson JR, Rohlman DS. Comparison of neurological health outcomes between two adolescent cohorts exposed to pesticides in Egypt. PLOS ONE | DOI:10.1371/journal.pone.0172696 February 23, 2017
Ismail AA, Wang K, Olson JR, Bonner MR, Hendy O, Rasoul GA, Rohlman DS. Impact of Repeated Exposure of Adolescent Pesticide Applicators to Organophosphorus Pesticides on Biomarkers and Neurobehavioral Outcomes, Journal of Toxicology and Environmental Health, Part A (2017) 80(10-12): 542–555. doi:10.1080/15287394.2017.1362612.
Tati, S, Fisk, J.C, Abdullah, J, Karacosta, L, Chrisikos, T, Philbin, P, Morey, S.M., Ghazal, D, , Zalzala, F, Jessee, J, Quataert, S, Koury, S, Moreno, D, Eng, J.Y, Glinsky, V.V, Glinskii, O.V, Sesay, M. A, Gebhard, A. W, Birthare K, Olson, J.R, and Rittenhouse-Olson, K. Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and In vitro Efficacy Analysis. Neoplasia (2017), 19: 716-733. doi: 10.1016/j.neo.2017.07.001
Karacosta, L, Fisk, JC, Jessee, J, Tati, S, Turner, B , Ghazal, D , Ludwig, R, Johnson, H, Adams, J, Sajjad, M, Koury, S, Roy, R., Olson, JR, and Rittenhouse-Olson, K. Preclinical analysis of JAA-F11, a Specific Anti-Thomsen-Friedenreich Antibody via Immunohistochemistry and in vivo Imaging. Translational Oncology (2018) 11, 450–466. doi: 10.1016/j.tranon.2018.01.008
Yang, E., Pavuk, M, Sjodin, A., Lewin, M., Jones, R. Olson, J., Birnbaum, L. Exposure of Dioxin-like Chemicals in Participants of the Anniston Community Health Survey Follow-Up. Science of the Total Environment (2018) vol. 637–638, 881-891. doi.org/10.1016/j.scitotenv.2018.05.074
Rohlman DS, Ismail A, Bonner MR, Rasoul GA, Hendy O, Ortega Dickey L,Wang K, Olson JR, Occupational Pesticide Exposure and Symptoms of Attention Deficit Hyperactivity Disorder in Adolescent Pesticide Applicators in Egypt. Neurotoxicology. 2019 Sep;74:1-6. doi: 10.1016/j.neuro.2019.05.002. Epub 2019 May 8. PMID:n31077682
Pittman GS, Wang X, Campbell MR, Coulter SJ, Olson JR, Pavuk M, Birnbaum LS & Bell DA (2019): Polychlorinated biphenyl exposure and DNA methylation in the Anniston Community Health Survey, Epigenetics. 2020 Apr;15(4):337-357. doi: 10.1080/15592294.2019.1666654. Epub 2019 Oct 14. PMID: 31607210
Butryn DM, Chi LH, Gross MS, McGarrigle B, Schecter A, Olson JR, Aga DS. Retention of polybrominated diphenyl ethers and hydroxylated metabolites in paired human serum and milk in relation to CYP2B6 genotype. J Hazard Mater. 2020 Mar 15; 386: 121904. doi: 10.1016/j.jhazmat.2019.121904. Epub 2019 Dec 16. PMID: 31901712
Anger WK, Farahat FM, Lein PJ, Lasarev MR, Olson JR, Farahat TM, Rohlman DS. Magnitude of behavioral deficits varies with job-related chlorpyrifos exposure levels among Egyptian pesticide workers. Neurotoxicology. 2020 Mar;77:216-230. doi: 10.1016/j.neuro.2020.01.012. Epub 2020 Jan 30. PMID: 32006538
Pittman GS, Wang X, Campbell MR, Coulter SJ, Olson JR, Pavuk M, Birnbaum LS & Bell DA. Dioxin-like compound exposures and DNA methylation in the Anniston Community Health Survey Phase II. Science of the Total Environment 742 (2020) 140424. https://doi.org/10.1016/j.scitotenv.2020.140424
VanEtten, SL, Bonner MR, Ren X, Birnbaum LS, Kostyniak PJ, Wang J, and Olson JR. Telomeres as Targets for the Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Polychlorinated Biphenyls (PCBs) in Rats. Toxicology and Applied Pharmacology 408 (2020) https://doi.org/10.1016/j.taap.2020.115264
VanEtten, SL, Bonner MR, Ren X, Birnbaum LS, Kostyniak PJ, Wang J, and Olson JR. Effect of exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) on mitochondrial DNA (mtDNA) copy number in rats. Toxicology, 2021-04-30, Volume 454, Article 152744. https://doi.org/10.1016/j.tox.2021.152744
Ismail AA, Hendy O, Rasoul GA, Olson JR, Bonner MR, Rohlman DS. Acute and Cumulative Effects of Repeated Exposure to Chlorpyrifos on the Liver and Kidney Function among Egyptian Adolescents. Toxics 2021, 9, 137. https://doi.org/10.3390/ toxics9060137
Rohlman, DS, Olson, JR, Ismail, AA, Bonner, MR , Rasoul, GA, and Hendy, O. Identifying and preventing the neurotoxic effects of pesticides. Advances in Neurotoxicology (2022). DOI: 10.1016/bs.ant.2022.05.001
Ghazal D, Zalzala F, Fisk JC, Tati S, Karacosta LG, Morey S, Olson JR, Quataert S, Dy GK and Rittenhouse-Olson K. Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models. Oncotarget, 2022, Vol. 13, pp: 1155-1164. https://doi.org/10.18632/oncotarget.28282
Eadeh H-M, Davis J, Ismail AA, Rasoul GMA, Hendy OM, Olson JR, Bonner MR, Rohlman D. Evaluating How Occupational Exposure to Organophosphates and Pyrethroids Impacts ADHD Severity in Egyptian Male Adolescents. NeuroToxicology Jan 5, 2023, 95: 75-82. https://doi.org/10.1016/j.neuro.2023.01.001
Rodríguez, D.; Barg, G.; Queirolo, E.I.; Olson, J.R.; Mañay, N.; Kordas, K. Pyrethroid and Chlorpyrifos Pesticide Exposure, General Intellectual Abilities, and Executive Functions of School Children from Montevideo, Uruguay. Int. J. Environ. Res. Public Health 2023, 20, 5288. https://doi.org/10.3390/ ijerph20075288