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School of Public Health and Health Professions
University at Buffalo (UB)
School of Public Health and Health Professions
Department of Epidemiology and Environmental Health
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FRY in Inhibiting EMT and Its Anti-Invasion/Metastasis Effects in Breast Cancer

This study will examine the molecular mechanisms of the FRY gene in inhibiting breast cancer progression and invasions, metastasis and explore the diagnostic and therapeutic effects of FRY in breast cancer.

Title: FRY in Inhibiting EMT and Its Anti-Invasion/Metastasis Effects in Breast Cancer

Principal Investigator: Xuefeng Ren, MD, PhD

Funding Agency: National Cancer Institute (NCI)

Period: 02/01/15 - 01/31/18

Abstract: The goal of this study is to investigate how the expression of the wild type or functionally mutated forms of the human FRY gene affects FRY’s ability in inhibiting EMT, tumor initiation, and metastasis, and to identify FRY-interacting proteins and FRY-associated signaling molecules.

Division of Environmental Health Sciences

The multidisciplinary Division of Environmental Health Sciences brings together students and faculty from across UB to integrate perspectives from a wide range of research areas.

Researcher Spotlight

ean Wactawski-Wende, PhD, principal investigator of UB’s Women’s Health Initiative (WHI) Center, discusses the significance of the WHI, one of the longest and most comprehensive studies ever done on postmenopausal women.

Jean Wactawski-Wende, PhD, principal investigator of UB’s Women’s Health Initiative (WHI) Center, discusses the significance of the WHI, one of the longest and most comprehensive studies ever done on postmenopausal women.