James R. Olson

PhD

Dr. Jim Olson.

James R. Olson

PhD

James R. Olson

PhD

UB Distinguished Professor
Research Professor
Department of Epidemiology and Environmental Health
School of Public Health and Health Professions
UB Distinguished Professor
Department of Pharmacology and Toxicology Emeritus
Jacobs School of Medicine and Biomedical Sciences

Research Topics

Assessing the health risks and biomarkers of exposure; effect and susceptibility to pesticides, air pollutants and persistent halogenated aromatic hydrocarbons.

Overview Publications News

Journal Articles

  • Gao L, Mutlu E, Collins LB, Walker NJ, Hartwell HJ, Olson JR, Sun W, Gold A, Ball LM, Swenberg JA. DNA Product Formation in Female Sprague-Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure.  Chem Res Toxicol. (2017) Mar 20;30(3):794-803. doi: 10.1021/acs.chemrestox.6b00368. Epub 2017 Feb 16
  • Ismail AA, Bonner MR, Hendy O, Rasoul GA, Wang L, Olson JR, Rohlman DS.  Comparison of neurological health outcomes between two adolescent cohorts exposed to pesticides in Egypt. PLOS ONE | DOI:10.1371/journal.pone.0172696 February 23, 2017
  • Ismail AA, Wang K, Olson JR, Bonner MR, Hendy O, Rasoul GA, Rohlman DS.  Impact of Repeated Exposure of Adolescent Pesticide Applicators to Organophosphorus Pesticides on Biomarkers and Neurobehavioral Outcomes, Journal of Toxicology and Environmental Health, Part A (2017) 80(10-12): 542–555. doi:10.1080/15287394.2017.1362612.
  • Tati, S, Fisk, J.C, Abdullah, J, Karacosta, L, Chrisikos, T, Philbin, P, Morey, S.M., Ghazal, D, , Zalzala, F, Jessee, J, Quataert, S, Koury, S, Moreno, D, Eng, J.Y, Glinsky, V.V, Glinskii, O.V, Sesay, M. A, Gebhard, A. W, Birthare K, Olson, J.R, and Rittenhouse-Olson, K.  Humanization of JAA-F11, a Highly Specific Anti-Thomsen-Friedenreich Pancarcinoma Antibody and In vitro Efficacy Analysis.  Neoplasia (2017), 19: 716-733. doi: 10.1016/j.neo.2017.07.001
  • Callahan CL, Pavuk M, Birnbaum LS, Ren X, Olson JR, and Bonner MR. Serum polychlorinated biphenyls and leukocyte telomere length in a highly exposed population: The Anniston Community Health Survey. Environment International (2017) 108: 212–220.
  • Callahan CL, Hamad LA, Olson JR, Ismail AA, Rasoul GA, Hendy O, Rohlman DS, Bonner MR. Longitudinal assessment of occupational determinants of chlorpyrifos exposure in adolescent pesticide workers in Egypt. International Journal of Hygiene and Environmental Health (2017), 220, Issue 8: 1356-1362.
  • Karacosta, L, Fisk, JC, Jessee, J, Tati, S, Turner, B , Ghazal, D , Ludwig, R, Johnson, H, Adams, J, Sajjad, M, Koury, S, Roy, R., Olson, JR, and Rittenhouse-Olson, K.  Preclinical analysis of JAA-F11, a Specific Anti-Thomsen-Friedenreich Antibody via Immunohistochemistry and in vivo Imaging.   Translational Oncology (2018) 11, 450–466. doi:  10.1016/j.tranon.2018.01.008
  • Yang, E., Pavuk, M, Sjodin, A., Lewin, M., Jones, R. Olson, J., Birnbaum, L.  Exposure of Dioxin-like Chemicals in Participants of the Anniston Community Health Survey Follow-Up.  Science of the Total Environment (2018) vol. 637–638, 881-891.   doi.org/10.1016/j.scitotenv.2018.05.074
  • Rohlman DS, Ismail A, Bonner MR, Rasoul GA, Hendy O, Ortega Dickey L,Wang K, Olson JR, Occupational Pesticide Exposure and Symptoms of Attention Deficit Hyperactivity Disorder in Adolescent Pesticide Applicators in Egypt. Neurotoxicology. 2019 Sep;74:1-6. doi: 10.1016/j.neuro.2019.05.002. Epub 2019 May 8. PMID:n31077682
  • Pittman GS, Wang X, Campbell MR, Coulter SJ, Olson JR, Pavuk M, Birnbaum LS & Bell DA (2019): Polychlorinated biphenyl exposure and DNA methylation in the Anniston Community Health Survey, Epigenetics. 2020 Apr;15(4):337-357. doi: 10.1080/15592294.2019.1666654. Epub 2019 Oct 14. PMID: 31607210
  • Butryn DM, Chi LH, Gross MS, McGarrigle B, Schecter A, Olson JR, Aga DS. Retention of polybrominated diphenyl ethers and hydroxylated metabolites in paired human serum and milk in relation to CYP2B6 genotype. J Hazard Mater. 2020 Mar 15; 386: 121904. doi: 10.1016/j.jhazmat.2019.121904. Epub 2019 Dec 16. PMID: 31901712
  • Anger WK, Farahat FM, Lein PJ, Lasarev MR, Olson JR, Farahat TM, Rohlman DS. Magnitude of behavioral deficits varies with job-related chlorpyrifos exposure levels among Egyptian pesticide workers. Neurotoxicology. 2020 Mar;77:216-230. doi: 10.1016/j.neuro.2020.01.012. Epub 2020 Jan 30.  PMID: 32006538
  • Rohlman DS, Davis JW, Ismail A, Rasoul GA, Hendy O, Olson JR and Bonner MR. Risk perception and behavior in Egyptian adolescent pesticide applicators: an intervention study. BMC Public Health (2020) 20:679 
  • Travis SC, Aga DS, Queirolo EI, Olson JR, Daleiro M, Kordas K. Catching flame retardants and pesticides in silicone wristbands: Evidence of exposure to current and legacy pollutants in Uruguayan children. Science of the Total Environment. Available online 10 June 2020, 140136
  • Pittman GS, Wang X, Campbell MR, Coulter SJ, Olson JR, Pavuk M, Birnbaum LS & Bell DA. Dioxin-like compound exposures and DNA methylation in the Anniston Community Health Survey Phase II.  Science of the Total Environment 742 (2020) 140424. https://doi.org/10.1016/j.scitotenv.2020.140424
  • VanEtten, SL, Bonner MR, Ren X, Birnbaum LS, Kostyniak PJ, Wang J, and Olson JR.  Telomeres as Targets for the Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and Polychlorinated Biphenyls (PCBs) in Rats. Toxicology and Applied Pharmacology 408 (2020) https://doi.org/10.1016/j.taap.2020.115264
  • VanEtten, SL, Bonner MR, Ren X, Birnbaum LS, Kostyniak PJ, Wang J, and Olson JR.  Effect of exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) on mitochondrial DNA (mtDNA) copy number in rats.  Toxicology, 2021-04-30, Volume 454, Article 152744.  https://doi.org/10.1016/j.tox.2021.152744
  • Ismail AA, Hendy O, Rasoul GA, Olson JR, Bonner MR, Rohlman DS.  Acute and Cumulative Effects of Repeated Exposure to Chlorpyrifos on the Liver and Kidney Function among Egyptian Adolescents. Toxics 2021, 9, 137. https://doi.org/10.3390/ toxics9060137
  • Eadeh, Hana-May; Ismail, Ahmed A; Abdel Rasoul, Gaafar M; Hendy, Olfat M; Olson, James R; Wang, Kai; Bonner, Matthew R; Rohlman, Diane S. Evaluation of occupational pesticide exposure on Egyptian male adolescent cognitive and motor functioning.  Environmental Research, 2021, Vol.197, p.111137. ISSN: 0013-9351; DOI: 10.1016/j.envres.2021.111137
  • Rohlman, DS, Olson, JR, Ismail, AA, Bonner, MR , Rasoul, GA, and Hendy, O. Identifying and preventing the neurotoxic effects of pesticides. Advances in Neurotoxicology (2022). DOI: 10.1016/bs.ant.2022.05.001
  • Ghazal D, Zalzala F, Fisk JC, Tati S, Karacosta LG, Morey S, Olson JR, Quataert S, Dy GK and  Rittenhouse-Olson K. Therapeutic efficacy of the humanized JAA-F11 anti-Thomsen-Friedenreich antibody constructs H2aL2a and H3L3 in human breast and lung cancer xenograft models. Oncotarget, 2022, Vol. 13, pp: 1155-1164.   https://doi.org/10.18632/oncotarget.28282
  • Eadeh H-M, Davis J, Ismail AA, Rasoul GMA, Hendy OM, Olson JR, Bonner MR, Rohlman D.  Evaluating How Occupational Exposure to Organophosphates and Pyrethroids Impacts ADHD Severity in Egyptian Male Adolescents. NeuroToxicology Jan 5, 2023, 95: 75-82. https://doi.org/10.1016/j.neuro.2023.01.001
  • Rodríguez, D.; Barg, G.; Queirolo, E.I.; Olson, J.R.; Mañay, N.; Kordas, K. Pyrethroid and Chlorpyrifos Pesticide Exposure, General Intellectual Abilities, and Executive Functions of School Children from Montevideo, Uruguay. Int. J. Environ. Res. Public Health 2023, 20, 5288. https://doi.org/10.3390/ ijerph20075288