Oral Microbiome and Periodontitis Prospective Study in Postmenopausal Women

This study examines associations among subgingival microbiota, personal characteristics, and periodontal disease presence, severity and progression in postmenopausal women.

Title: Oral Microbiome and Periodontitis: A Prospective Study in Postmenopausal

Principal Investigator: Jean Wactawski-Wende, PhD

Co-investigators: Michael LaMonte, PhD, MPH, and Amy Millen, PhD

Funding Agency: National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health (NIH)

Period: 08/01/14 - 07/31/19

Abstract: This study proposes to conduct a 15-year post baseline clinical examination in a defined cohort of older postmenopausal women, who already completed baseline and 5-year examinations, to examine prospective associations among subgingival microbiota, personal characteristics, and periodontal disease presence, severity and progression over time. 

Division of Environmental Health Sciences

The multidisciplinary Division of Environmental Health Sciences brings together students and faculty from across UB to integrate perspectives from a wide range of research areas.

Researcher Spotlight

Jean Wactawski-Wende, PhD, principal investigator of UB’s Women’s Health Initiative (WHI) Center, discusses the significance of the WHI, one of the longest and most comprehensive studies ever done on postmenopausal women.