Randomized Trial of Cocoa Flavanols and Multivitamins in the Reduction of CVD and Cancer

The study will test whether the effect of a concentrated cocoa extract can help reduce heart disease and stroke and whether commonly used multivitamin supplements can help reduce the risk of cancer, particularly in older women.

Title: Randomized trial of cocoa flavanols and multivitamins in the reduction of cardiovascular disease and cancer (referred to as COSMOS study).

Principal Investigator: Jean Wactawski-Wende, PhD

Funding Agency: Brigham and Women's Hospital, and Mars Symbioscience Inc.

Period: 08/02/16 - 12/31/18

Abstract: The study will test whether the effect of a concentrated cocoa extract can help reduce heart disease and stroke and whether commonly used multivitamin supplements can help reduce the risk of cancer, particularly in older women. Participants from The Women’s Health Initiative (WHI) will randomized into the study and assigned to one of the 4 WHI Regional Centers for follow-up and outcomes documentation.

Division of Environmental Health Sciences

The multidisciplinary Division of Environmental Health Sciences brings together students and faculty from across UB to integrate perspectives from a wide range of research areas.

Researcher Spotlight

Jean Wactawski-Wende, PhD, principal investigator of UB’s Women’s Health Initiative (WHI) Center, discusses the significance of the WHI, one of the longest and most comprehensive studies ever done on postmenopausal women.