Cardiovascular Disease Biomarkers Analysis of Three Novel Markers in the BCOPS Study of Police Officers

Analysis of three biomarkers associated with cardiovascular disease could provide associations between psychological stress and subclinical CVD in police officers.

Title: Analysis of Three Novel CVD Markers in the BCOPS Study

Principal Investigator: John Violanti, PhD

Funding Agency: National Institute Occupational Safety and Health (NIOSH)

Period: 08/18/14 - 08/17/15

Abstract: This study measured three biomarkers known to be associated with cardiovascular disease (CVD) and stress: Homocysteine, Neuropeptide Y, and Retinol binding protein-four. Measurement of these novel biomarkers will permit the examination of associations with 1) police-specific stressors (i.e. shift work, psychological stress) in a known high stress occupational group, and 2) subclinical CVD in a population known to have adverse levels of CVD risk factors. The information obtained from this study could provide new insights for the association between psychological stress and subclinical CVD.