The parasite Toxoplasma gondii infects about 20 out of every 100 people in North America by the time they are adults. In healthy individuals, this rarely causes problems, however, Toxoplasma gondii infections cause t-cells to cause inflammation instead of preventing it.
When DNA is damaged by stress, cells activate Poly ADP Ribose Polymerase 1 (PARP1) as part of the repair process. Partially inhibiting PARP1 using chemicals has beneficial effects including increasing anti-oxidant levels in the cells. This study aims to understand how inhibiting PARP1 can help in the treatment of blast-induced traumatic hearing loss and tinnitus.
This project aims to reduce the risk of frail adults falling. The study quantifies the effects of the one-year community education program in a reduction in hospitalization and medical expenditure due to fall injuries.
Located in the School of Public Health and Health Professions since 1999, CIRRIE facilitates the sharing of information and expertise between the U.S. and world-wide partners to improve the conditions of people with disabilities.
Susan E. Bennett, EdD, will examine the effectiveness of Dalfampridine, an FDA-approved medication to improve walking in patients with multiple sclerosis, when combined with a physical therapy program.
Investigators studied the effects of a resistive respiratory muscle exercise training program on respiratory muscle strength and endurance, as well as fatigue, exercise capacity, and functional performance, on Multiple Sclerosis patients.