Behavioral Evidence of Tinnitus and its Correlation with ABR Wave Metrics in Chinchilla Induced by Blast Injury

Making tinnitus research more accurate by finding new ways to measure behavioral evidence of tinnitus in chinchillas. 

Six brain scan intensity maps show concentrations of a naturally occurring neurotransmitter.

Six brain scan intensity maps show concentrations of a naturally occurring neurotransmitter.

Principal Investigator: Vijaya Prakash Krishnan Muthaiah, PT, PhD

Awarded: July 2020

Sponsor: Department of Defense

Description: To characterize the behavioral evidence of blast-induced tinnitus in chinchillas using Preyer’s reflex (flexion of pinna) as a reliable marker of the startle response along with whole-body movement and by adopting a new statistical approach, rather than by simple averaging of measured pre-pulse inhibition (PPI) values.