Season 1: Health Equity
Season 2: Nutrition
Season 3: Substance Use Disorders (SUDs)
Season 4: Environmental Health
In this episode of Buffalo HealthCast, we sit down with Dr. Meng Wang, an environmental health scientist, to explore the hidden dangers lurking in the air we breathe and their impact on lung health. Dr. Wang reveals how baseline levels of pollutants like PM 2.5, ozone, nitrous oxide, and black carbon contribute to the progression of emphysema.
Dr. Wang emphasizes the critical need for targeted policies to protect vulnerable populations. He also discusses accessible solutions, including DIY air purifiers, and highlights the importance of public education and awareness about air quality in our changing climate. Don't miss this vital discussion on the intersection of air pollution, health, and climate.
Vennela Damarla: 0:04
Welcome to another episode of Buffalo HealthCast. I'm Vennela Damarla Podcast Producer, and today we have Dr. Meng Wang, a leading expert in environmental health research. In this episode, we will be discussing Dr. Wang's research, which focuses on impact of air pollution, particularly ozone, on lung health and the progression of emphysema. Whether you are a health care professional or interested in learning more about air pollution, this episode of valuable insights. Dr. Wang, thank you so much for joining us today. So before we get into your interesting research. Can you tell us a little bit about your background and what motivated you to pursue this research? Yeah,
Dr. Meng Wang: 0:48
Sure, so. My name is Meng Wang. I am an environmental health scientist. Most of my research focuses on for assessment of air pollution and also trying to understand how air pollution could cause adverse effect of human health. Well, I did modeling work, and has been involved in several large collaborative studies focusing on mostly focusing on respiratory and cardiovascular health. The motivation of me to involved in this study actually has been for a long time. So my background actually originally from atmospheric science, not related to health at all. So at that time, I'm curious about like the chemistry of atmosphere, and then realizing some gluttons are really toxic, making me feel like how this chemicals could affect human health. So that moves me towards the health field. So it's a learning process for me for several years, and then I try to involved in some large cohort studies in there. I can collaborate with some physicians there, environment epidemiologist there, so I can leverage my experience in atmospheric science, but also find linkage to epidemiology. So that is why nowadays my I can my focus is on air pollution related epidemiology.
Vennela Damarla: 2:32
It's wonderful. Dr. Wang, so let us start with some questions. How do you see in the section of climate change and air quality evolving, and what implication does this have for respiratory health in the future?
Dr. Meng Wang: 2:47
Yeah, so this is very big topic. I would say that climate change is general term, which means that it can be related to many extreme weathers like increased temperature, right? And then increased temperature can cause extreme heat and cold storms and etc. And this climate factors can actually impact air quality. So one typical example is wildfire, because now you can see that when the temperature goes up, the drought goes up, then it's possible that burning is getting more frequent, right, especially when we see lots of wildfires happen in the West Coast of the United States as well as in the Canadian country. So this is definitely indirect impact of climate change on air quality and the problem of wildfire smoke is that in the US and Canada, government has making a long term effort to reduce air pollution by many policies. Right. Clean Air Act is very successful, but because of climate change and that wildfire could offsite the effort of Clean Air Act and talking to the future. So you know, the IPCC has developed many climate models globally to try to pre-project how temperature or climate factors as well as air pollution, could change in the next 50 or 100 years later. And what they find is that the pollution level can go high if there's no ending control on human activity. 80 or like human emissions, right? So, but they also simulate like, if people can control the greenhouse gasses, which is the leading cause of increased temperature. So, if they can control the greenhouse the emission of greenhouse gasses in different levels, then it's possible that temperature will go down in many years, and also the clean air. We can still see it's all about the like interactions between human efforts and the climate.
Vennela Damarla: 5:41
Thank you. Dr. Wang, and I would completely agree with you regarding the wildfire, and this is the topic that you've been teaching us in the class too. So yeah, moving on to the next question. Could you briefly elaborate on how prolonged exposure to air pollutants such as ozone pm 2.5 and nitrous oxide affects lung health and function.
Dr. Meng Wang: 6:07
Yeah. So usually, when we talk about air pollution, we say that air pollution have two effect. One is called a shorthand effect. Another one is called long term effect. The shorthand effect, in fact, it's like when air pollution goes high very rapidly, like wildfire event, then people may get disease immediately, right? And that is really because people already have some pre-existing disease. So we call it like a harvest of human but for long term effect air pollution, just because everyone breathes air, right? So it's kind of explored to take life long. Many studies have already find that. So if people persist the exposed to air pollution for many years, it's possible that the pollution could increase their risk from the beginning for the healthy people, and then gradually increase their biological pathways and clinical symptoms and eventually increase the disease and come back to the respiratory disease. Actually, you can see that air pollution usually enters our bodies through respiratory system, right through respiratory tract. Respiratory disease definitely is most directly impacted by air pollution in terms of the pollutant. Though we know that particulate matter, and also our most important one. Particulate matter is important because they are so tiny that they can easily enter into our respiratory tract. The train here area is more like the connection between the lung and our circulation system. So once this, if the particles are more enough, it can enter into our circulation system. And of course, cardiovascular disease, that means that particulate matter not holding a factor with BFP disease, but also increased risk of cardiovascular disease back to Otto. So autumn is the gas pollutant. So autumn is usually enters into our affecting our lung. But OM is very active pollutant. It's easily interact with other pollutant. So there's once Otto enters into our respiratory tract. It can cause lots of chemistry happen in our lung. So this chemistry may release a new pollutant and then increase the risk of our lung disease. So this is a basic understanding for now in terms of how, PM, 2.9 organ may cause respiratory disease.
Vennela Damarla: 9:05
Well, I really appreciate how you have detailed everything. Dr. Wang, so which pollutant do you think have a stronger association with lung disease progression compared to other pollutants?
Dr. Meng Wang: 9:20
So I would say that I cannot make a judgment so far. So you can see that different studies have different findings. Some studies, they find that PM, 2.5 may be the most important one. Some define also, or some study defined WC or other pretense. So that's really depending on the population, study area and also monitoring technology, Explorer assessment, I would say particulate matter, fine particulate matter, or maybe the most important risk factor for respiratory disease so far. Up because there's many studies have shown this consistently show this results.
Vennela Damarla: 10:07
Okay, so you have mentioned about the long term effects as well as the short term effects of air pollution. So how do you think the long term effects of cumulative exposure to air pollutants differ from the short term impacts of acute exposure on respiratory health?
Dr. Meng Wang: 10:25
Yeah, that's a great question. Usually, if we think about shorthand exposure, we compare. So if we think about shorthand exposure, we compare whether the exposure on the day that has a high level of pollution, as more people get disease, compared to the day another day, next to the day before and after this day Where the concentration is low, lower number of people get delays. So that is comparison of understand the shorthand effect of air pollution. I would say that shorthand effect happens because air pollution, important air pollution events happen. So some days when pollution happens, high pollution level in certain days and another days it goes up. So in that way, when the concentration immediately gets high. So people who has disease already respiratory disease, for example, so they will not tolerant to that high level of pollution, and then it's possible that they may get immediate disease sequence. So one several typical examples would be like people who had a COPD, they may have severe symptoms, getting more severe recipients during the high level pollution days, and then this may cause them to go to the hospital immediately, or go to the or more severely, may cause people die. So all this happened at very short time period, but it usually affects the people who already have pre-existing disease, or had a like low immune system, right? Or have some Alexa sample population, but long term, back to the long term exposure to air pollution and health. This is maybe different to mechanism. So long term exposure, we don't consider like extreme air pollution event. It's more like a average exporter over long term period. So it's like people always we compare people living in high pollution area to the people who live in low exposure location area, and follow them up and say, better they develop these disease so, because it's follow so long period, and people can be from air pollution And gradually increase their for example, their like biological response, for example, like without it, can increase the risk of inflammation, passive stress, and this inflammation, if it's keep going on the inflation and lead to certain subclinical diseases. So for example, their lung function may go down, their blood pressure may go up, right? And these are the like preclinical, subclinical symptoms. So for respiratory disease, one typical example is emphysema. Emphysema is a structure change of their lung, so once it happened, it's not reversible, right? And and also for cardiovascular disease, we have a term called as those sclerosis, meaning that the plug build up in cables vessels, and when it gets more serious, the plot cannot be removed, right? Unless you take us surgery. So this is how air pollution can gradually affecting the development of disease.
Vennela Damarla: 14:26
So do you think short term exposure to air pollution with the pre-existing conditions can cause irreversible lung damage?
Dr. Meng Wang: 14:35
It's possible. I would say that, like I said, when short term air pollution event happens. It can worsen the lung disease or lung structure in that way. I say it's possible to cause some in reversible disease, but not like long train exposure, because the very support disease.
Vennela Damarla: 15:01
What were the most surprising findings regarding the association between the air pollution and lung health in your study?
Dr. Meng Wang: 15:09
Let me first introduce the study a little bit. So this is a multi side study in United States. So United States, we select 680s and then each city recruit 1000 people, starting from 2000 and follow them up all the way until 2020, so it's like a 20 years follow up period. And during this period, people will take CT scans apart about every four or five years and also take lung function test at the same time. So it's like a repeat measurement over time. The good thing of this study this size, like it's longitudinal follow up study with repeat measurement, so you can really track the progression of lung disease over time. So using CT scan, it can use physiological technology, quantify the area where the lung has abnormal change, have normal change, can be converted to this decide whether or severe the Emma sigma symptom is. So the larger area the abnormal area is, then the most Emma sigma is we expect. So in this case, we can see that the whole the emphysema progress over time and in the meantime. So the group I working with at University of Washington, we developed high resolution air pollution model. High Resolution means that it can predict air pollution bi weekly, and also at every single location of the participants. So each participant will assign unique Data Explorer value to them, so we can really track their air pollution data longitudinally for these participants as well. So both explorer and outcomes are longitudinal data, so we can link them together to see okay whether people living or exposed to high level of air pollution in this area also has faster progression of emphysema over these 20 years and yeah. So we focus on several key proteins. One is PM, 2.5 or five particulate matter. Second one is an o2, oxides of nitrogen, which is indicator of traffic emission. Third one is autumn, which is a secondary pollutant, very important to respiratory disease, and the last one is black carbon. So surprisingly, we actually find that all these pollutants at baseline are associated with faster progression of eczema over time. So baseline explorer means that the Explorer level assigned to the time as a time when people are recruited in 2000 so what it means is that at the time, if people exposed to high levels of game, 2.5 or ozone, for example, at the beginning, in early years, when they recruit this impact could be lifelong, already impacted their progression over time. So this is important, because you know that air pollution goes down right? So this means that people, like older people, may not really get benefit from really get benefit from clean air at the beginning, so at that time, the the bad air and already trigger their respiratory disease.
Vennela Damarla: 19:16
Well, your study also tells that while concentration of particulate matter 2.5 and oxides of nitrogen decreased during the study, but ozone levels remain a concern. So what factors do you think that contribute to the increased level of ground level ozone?
Dr. Meng Wang: 19:34
Yeah, so this, this is good question, and also complicated story. This is back. We'll be back to talk a little bit background about atmospheric chemistry. So you know, for fine particulate matter, I would just say at least a half of the particular PM, 2.5 man made sources like. Our vehicle emissions, our industry emissions, cooking, all generated particles. But autumn is different. Autumn is a secondary pollutant, which means that their product formation of autumn is not dependent on the lack of a man made emission. It's based on the chemistry. It's a product of primary pollutants like pm, 2.5 oxides of nitrogen, this pollutant. So if the Clean Air Act, basically the at the beginning is to control memory sources. But if you control memory sources, you control the emissions from pollutant generated from memory sources such as oxygenator such as oxides of nitrogen, but you cannot control OSM because ozone is not directly needed by the any of these manmade sources actually back to the chemistry. So autumn formation is very complicated, but in some circumstances, lower level of oxides of nitrogen and increase the level of autumn. So that's why control also. It's very challenging so far, even though in the US there's many policies to control autumn, but it's very difficult. You can imagine, like during the COVID pandemic, there's many industries. There are many people do not come out, so they do not drive and we have significant reduction of traffic emission, they will get better, much better air quality in terms of PMG on the fire size, nitrogen. On the other hand, we have a worsened ozone situation during this period. So it's complicated story back in in terms of chemistry and when link this flu trend to health effect, then that could be different mechanism as well.
Vennela Damarla: 22:11
Yes, so despite the alarming findings, what gives you the hope for improving the lung health outcomes in the context of raising air pollution levels.
Dr. Meng Wang: 22:21
I would say that overall air pollution, air quality is getting better overall, but we do see that it's unevenly distributed or anchored, disproportionately affecting different people, especially some like low income communities, they are historically exposed to close to industry or like those two traffic area, so their pollution level may not really receive the adequate benefit from the Clean Air Act. So in that way, their air pollution level may not really goes down that rapidly, and their health effect may be of concern now in the United States, and back to the what we can do to improve lung health. So I think there are two aspects we need to think about. One is the policy this level of policy makers, they may the policy should focus more on this, like vulnerable population, underserved community, this population, not focus on everyone, like previously in the act. It's like overall entire country, but now it should be more specifically focused on underserved community to reduce their level of solution. So we can see that many sponsors like the EPA and I actually invest the money to find to help communities to improve their resilience to air pollution. One thing they can do is that have education to people, because people in there, they may not well educated, knowing how to if air pollution event happens, what we should do, right? So like normally, if wildfire comes, then people will receive alert. They will have access to internet, watch TV, and then they know that, okay, next day, the model will have wildfires that we need to do something. But for low income communities, they may not know this they may not have access to know this knowledge. So in that way, the government should have some policies to help them increase their alert to this event, helping them, giving them resource to get access to this alert. On the other hand. I think the prevention could be at an individual level. Air purifier has many studies have evidence that air purifier can reduce air pollution, especially particulate matter, very effectively. But the problem is that this technology only be applied quite a lot of high income communities, but for low income communities, people may not afford this air purifier, but luckily, now there are some studies trying to build up like the DIY air purifiers. It's very simple. You just use the future air filter, built up a box and then attach a box fan. This could be a very simple air purifier, but more efficient than commercial one, and it cost like 1/3 or half price of the commercial air purifier. This is a very good example may be possibly used to increase people's health in terms of recipient days.
Vennela Damarla: 26:11
Yeah, so DIY, air purifier, this is something new that I've learned today. Dr Wong, so the population such as, have low income communities and the population living near industries. How do you protect this population from air pollution? What can be done?
Dr. Meng Wang: 26:33
Like I said, this effort that should be done by both policy makers and individual like community residents. So now we have some studies find we have some connections with the Buffalo African American community, and we know that they are living close to many of the communities are close to major road or too close to highway. So what we are hoping to do is that, first to increase their education level, like holding some event to the community, and to introduce, like, given a background about air pollution, what is so in that way, when air pollution event comes, they can know about this. And also, another way to do is like people. The problem for people is that they don't know their explorer level, what the exposure level is. So our pilot study is doing now is to give them the low sub cost sensor and monitor. The local sensor monitor is cheap, like a 30 to 50 bucks, but it can visualize the readings of levels of evolution as well as the color to indicate like green, yellow, red to indicate whether they should be concerning about their indoor air quality. So in that way, we hope that this will help the community people to get early alert of their indoor air quality problem, and we also try to use, like I mentioned, a DIY air purifier to see how effective it is to improve their health. And what's normal, I think now in this study, is that we notice that the sample population, for example, we typically focus on elderly participants. Elder participants, they they may have, like a decline memory, so they may not really know that. Okay, I should check the air sensor readings and when should I turn it on? When should I turn it off? There's really a lot of burden on them, so what we do is that we do it like a smart control system. We can use the air sensor to determine when we can switch on, switch off, their blog, and the plug will connect to the beautiful air purifier. So everything could be automatic, so we can set up a safety level to them. Once the level is above the safety level, then automatically turn on the air purifier. So in that way, we hope that this can help people, especially older people, or the self population, improving their health.
Vennela Damarla: 29:46
Well, moving on to the next question, so how effective would be the Clean Air Act? You think the Clean Air Act would help people to protect from the air pollution with pre-existing. Conditions, respiratory conditions, older individual and people from low socio economic status?
Dr. Meng Wang: 30:08
Yes, so I want to say that the original design of Clean Air Act is trying to reduce the overall emission of air pollution. That's including the traffic industry, everything this, because there's many policies behind it trying to reduce the manmade emission so the fusion level goes down rapidly, I would say over the past 30 years. Yeah, so like 30 years ago, the pm treatment level could be about over 50 microgram per cubic meter. Now it's below 10. So it's a remarkable achievement to the air pollution. So definitely I believe that because air pollution goes down so much, so much so there's a huge benefit on respiratory health. And actually some studies already evident your evidence. For example, one study conducted in California works on children's health. So recruited school children in elementary school and in seven sites, and then they follow them up for multiple years, and they check whether reduced air pollution is associated with better lung function, increase the lung function. And they did find a significant association, and that's very encouraging and clear evidence supporting that a clean air effect is very effective, but back to like the benefit applied to everyone, but not equally applied to everyone. So some places may have, for example, far away from the sources, may have less issue, but other resources, lots of communities near industry and that, so they also need to consider about the economics. So in that way, there's always fight between industry and the local community, the main the industry may not want to reduce their emission a lot, but community people concerned about it. So this about environmental justice issue remains, still remains in the United States, and that's also one of the most important topic.
Vennela Damarla: 32:44
Now, okay, so what do you think are the biggest misconceptions about the effects of air pollution and health and how can we educate the public?
Dr. Meng Wang: 32:55
But what I can say, one thing probably people may overlook or negligible is that? So in some areas where air pollution is low, people may feel that they are pretty safe. There's no problem. Air pollution has no effect on them at all, that they don't care about air pollution at all. I think on one hand, it's good that air pollution is air quality is good. They may have other environmental issue that they can they should be careful. But on another hand, current studies, they did not find, suggest that there's a safe threshold of air quality, of air pollution health. It means that even air pollution level is very low, there's a still adverse effect on human health. We cannot say that. Okay, air pollution below five microgram per kilometer, you don't need to care about it. There's no impact on you. Even it's lower, still have impact. It's like pathogenic compounds. You know that's constant. Genetic compound may cause cancer no matter how low the level is, and always cause cancer. Have agreed, can always increase the risk of cancer. Thing for air pollutant, we cannot say that, okay, areas are pretty air quality are pretty good, and then people don't need to care about it. So I think that's something we need to educate people that air pollution should always be care about, even though you are in a clean air location.
Vennela Damarla: 34:45
Yes. Doctor Wang noted, like you said, even the air pollution is lower, it can have an impact in a long run, yeah. So in your view, how significant is the role of ambient air pollution as a risk? Factor for chronic lung diseases compared to other known risk factors, such as smoking or occupational hazards.
Dr. Meng Wang: 35:09
Yeah, so I would say that that's depending on what's the level of population you mentioned about. So if we talk about individual level, like for single people, maybe many other factors. Smoking may be very important risk factor for these people. And if people have poor dare to have it, they may there may be a big problem. But when we talk about population level, meaning that including all the people, putting all the people together, and put and then we reckon the risk based on differential risk factors, then air pollution would be top leading factors. So the long set general, you know loan set is like the top medical general, set general release, the top rank the risk factors that cause people dying every two or three years. And if you read the long set general, you will see that the ranking of air pollution, typically, PMG point goes up year by year. So like five years ago when I read the long set general five Part Two, the matter already ranked as number five of risk factor that may cause people time. The reason is that, or I would say that opposite is the risk factors are smoking, like blood high blood pressure, so all these traditional risk factors. The reason why air pollution because so many people die, but its level is actually low. The reason is really because all the people are exposed to air pollution compared to a few people mode. So because everyone are exposed to air pollution, potentially, the number of people get disease could be substantial. If you sum up these people who get disease as number could be really huge. And also then, if you look at the ranking in the most recent year, actually, image open the file is now top one or top two. So it's now the top of top of the top is the ranking of this risk factors. So the reason for it, in my understanding, is that many of the traditional risk factors has better control because people know how to do it, and it's very effective now, adding more effective now, and we have, like, a smoking control policy, and we have a better health care so in that way, traditional risk factors has been controlled, and the people get this disease because of the stresses factor. But now for air pollution, even though air pollution level goes down, also in many developed countries, I would say, not all the countries, but the population size going up, so it's offset the benefit of air pollution. So eventually the number of people die because of air pollution has been the ranking go up. Okay, so I hope I explained this clear.
Vennela Damarla: 39:04
Yes, Dr. Wang, you, you have explained it very clearly. You have mentioned that PM, 2.5 is the leading air pollutant right now. So are there any measures taken to control a PM, 2.5 air pollutant?
Dr. Meng Wang: 39:21
Yes, so PM, 2.5 is not like a new star. It's like an old friend for us for many years. So I would say that probably 1980s so there's the first study called the Harper six city study. That study, they identified that the five particulate matter is strongly associated with mortality in a cohort study. From there, people know that particulate matter is um. Important risk factor. And from then on, many studies prove this concept. And then EPA realized this problem. So for the Clean Air Act, controlling PM, 2.05 is one of the major task. So I would say that in the United States control. PM, 2.5 this effort keep going on for many years. There's lots of policies at like federal level, state level and country level, community level, individual level to control the pm 2.54
Vennela Damarla: 40:44
It's really awful to know that pm 2.5 is increasing mortality rate. And it's also good to know that there have been a lot of measures and efforts by the government and then acts and policies to control this. So despite the challenges presented by the air pollution, what gives you hope for the future of lung health and public policy?
Dr. Meng Wang: 41:08
Yeah, I would say that the current policies are still effective in reducing em 3.5 so now you know that the standard, the pm 2.5 standard, by EPA, become more rigorous every 10 years. So every 10 years, then EPA will re evaluate their policy, the standard, pm 2.5 standard, whether it's adequately protected human health. So very recently, I think this year, EPA updated uscpa updated the pm 2.5 standard, saying that the annual average level of pm 2.5 should be below nine micrograms per cubic meter. Previously the level is 12 microgram per cubic meter. So this is drop. And given that the level is already low, and they still want to reduce this level, so you can see that it's it's like reduce the pollution by 25% it's a very ambitious policy, and I think this policy will making sure that improving Air Quality will still be beneficial to our respiratory health, cardiovascular health, human health. Well, on the other hand, I think even though, in addition to the policy, the classic or traditional policy, like traditional source of air pollution, we may think more about controlling new source of pollution. Like I mentioned, how we can control climate change. We can slow down the climate global warming this step, just like I said, climate change have indirect impact on air quality. So for example, now government has some policies other than carbon neutralization. It's basically to reduce the carbon consumption, and in that way, the emission of greenhouse gasses will be controlled and the temperature, hopefully the temperature will be flattened out or go down in the future, and then in that way, solution level goes down, in the same case of the greenhouse gasses. So that's another angle I think should be care about myself, air pollution control and the beneficial to respiratory disease.
Vennela Damarla: 44:06
Thank you, Dr. Wang for providing a great summary. So what final advice would you give to our listeners about protecting their families from air pollution?
Dr. Meng Wang: 44:17
Yeah, so for families, I think I would suggest that everyone should know some basic about air quality. First, we should know that everyone are exposed to air pollution. So if there are many resources, actually, the researchers, government are making effort to provide many resources to community residents, helping them to understand what's the level it is. I can come up some resources, hopefully can be helpful. So one is that uscp have website. It showing the level of air pollution based on their air monitoring stations there, and when you train station will join visualize the level of pollution. For example, in New York State, the US, nysdc, they have a website, and they keep updating the level of air pollution hourly. So this could be a resource to look at, okay, whether your residential location is safe or not. Another resource is that, like the US, CDC and EPA, they develop some map for the environmental justice map or social vulnerability index map. So what this map is useful is that it gives you every single community some the information about what's the leading environmental risks are in this community, because not all the communities have the same environmental problem. Some community may have problem of noise. Explore. Some of them may have like air pollution. Some of them may have like the waste water, for example. So this map will giving you a sense about what's the problem in your environmental problem in your community. This will help people to understand this. And another one, I would suggest, is that if people identify that air pollution is a problem, or you're concerning about air pollution problem, the easiest way is to use air purifier. It's very effective to remove air pollution. And also, there's now several community organizations invest they are helping residents to solve the environmental problems. So there are many approaches hopefully can help the family to first know their risk of air pollution, Second, take actions to prevent air pollution. So
Vennela Damarla: 47:09
Are there any final concluding thoughts you would want to share with us Dr. Wang?
Dr. Meng Wang: 47:14
Well, I would say that air pollution is always a problem, but the problem of air pollution as angle has been shifting from traditional industrial control towards Eco community problem of air pollution, then not towards climate change, impact on air pollution and the human health. So it's like, keep going on story, and we are making effort to understand the problem, helping people to solve their problem and hopefully to improve their health.
Vennela Damarla: 48:02
Thank you so much. Dr. Wang, it's been really an insightful session. Stay tuned for another episode on Buffalo HealthCast. Thank you.
Welcome to Buffalo HealthCast, the official podcast of the University at Buffalo's School of Public Health and Health Professions!
In this episode, we speak with Dr. Yohane Phiri, a postdoctoral research associate in the Department of Epidemiology and Environmental Health, about his groundbreaking research on how environmental factors shape early childhood development. Dr. Phiri discusses the profound impact of chemical exposures, pollutants and psychosocial stressors on pregnancy and preterm births.
Tune in to discover how these critical environmental influences can affect the earliest stages of life and the potential long-term outcomes for both mothers and their children.
Yohane V.A. Phiri, PhD
Vennela Damarla: 0:02
Hello there. Welcome to Buffalo HealthCast, the official podcast of the University at Buffalo's School of Public Health and Health Professions. Join us as we delve into the latest research from Dr. Yohane and uncover how factors like environment, chemicals, psychosocial stressors can shape the earliest days of child life. Whether you are a parent or a health care professional or simply curious about the intersection of environment and health, this podcast will guide you in understanding how we can nurture healthier future from the very beginning. I'm Vennela Damarla, MPH student and also production assistant for Buffalo HealthCast. Today we have Dr. Yohane Phiri with us, who is a post doctoral research associate in the Department of Epidemiology and Environmental Health. It is so wonderful having you here, Dr. Yohane, let's start with some introduction. Dr. Yohane, can you tell us a bit about yourself and your work.
Dr. Yohane Phiri: 1:02
Yeah, thanks so much for having me on this podcast. So as I've already said, my name is Dr. Yohane Phiri. I'm currently postdoctoral research in the Department of Epidemiology and Environmental Health. I work under this provision of the Chair of the School Professor Pauline Mendola. It is an honor when you invited me to join you in on this podcast, to share a number of experiences that I have developed through my endeavor and understanding environmental exposures and specifically focusing on perinatal and periodic Health to health epidemiologists whose research focuses on environmental exposures, I specifically examine what type of environmental characteristics used to be, the air pollution affect perinatal and pediatric health. I have the skills now by I'm able to integrate a number of large data sets in the US that includes data from Medicare, Medicaid and the birth registry data. I link these with air pollution and our environmental pollutants, so this allows us to examine the effects of various developmental exposures and maternal and neonatal health outcomes. These include preterm births, low birth weight status and issued within our NATO Intensive Care Unit admissions. And I'm also involved in other projects, prospective projects, one of which is trying to employ secondary data from a completed project that was funded by the NIH, started project that was conducting Birmingham and University of Alabama, and we try to investigate asthma control status in women during pregnancy. These projects are vital because they generate insights that both theoretical, but also in the reward decision making, because if we understand the role that environmental exposures have in worsening, in our gravitating the conditions of pregnant women themselves, but also their offsprings and the long life risks, the wrong life impact of these exposures, this will be very important in the design of policies which would help in deducing or which would help in controlling some of these major health determinants. So to epidemiologist, outwork with someone who is doing dental medicine, I'll work with a nutrition epidemiologist. Together, collectively, we have that ability to develop or come up with policies or research that could be used to address some of the major challenges that our communities are facing. We should understand that public health is a complex issue, and there are a number of complex ways, the number of ways that we can bind to deal with such type of challenges. So in general, I think I use both qualitative and quantitative research methodologies in most of the projects that are taken. Thank you.
Vennela Damarla: 4:19
That's wonderful. Dr. Yohane, what made you interested in the topics you study?
Dr. Yohane Phiri: 4:24
Yeah, so thank you very much for this wonderful question. Um, first of all, I'm not originally from the US. I'm a Malawi. Malawi is located in the south eastern part of Africa. My journey into studying about mental health exposures, I think, began in the year 2003 when I joined the University of Malawi in those days. Now it's called Malawi University of Business and Applied Sciences (MUBUS), where I majored in our mental health at that time, I specifically majored into looking at a. Occupational Health. And in Malawi, there's a region known as Mulanje, people grow tea, and there were a number of increasing instances of people reporting injuries, a number of operational exposures in their work environment. So my undergraduate degree program really focused on trying to find factors that were associated with the prevalence of this disease, I mean, these instances amongst the typical workers in Mulanje. But through the course of doing that research, I noticed that it wasn't all about the occupation hazards that were exposed to, but also to do with the living environment of the people at that time, I'm not sure of this status. Now that some of the changes are being made, there have been policies that have been revised to address these issues. But then a number of living involvement factors were associated with a number of outcomes that the tea picking workers, the people that picked tea or plant tea in the estates were exposed to so from there, my attention kind of shifted, and I initially grew interest to understand a number of factors associated with our living environment. This curiosity led me to go and apply for funding and do my master's degree in environmental Mental Health And Urban Studies, which I did in Kojaheri, investor in Turkey. And I also did an internship in sustainability science with investor of one in Germany. The purpose of all this was just to try to see how our living involvement shapes most of the things that determine our health. And through that curiosity, I ended up pursuing a PhD program, which I did in Taiwan, Taipei Medical University. And I finished my PhD studies in 2023 and in Taiwan, that's where I think I kind of deeply developed a passion to understand, to say, I focused on women specifically because I worked on a project and there were a number of interesting findings that that project is called the longitudinal examination across prenatal and postnatal health in Taiwan. It is one of the most wonderful projects that I wave awake on, and it drives my interest in understanding the role of environmental exposures and outcomes in pregnant women and children. So from there, then I think I specifically focused on understanding environmental pollutants, that's indoor air quality, indoor air pollution and also health in both the pregnant women and the children. That's how my journey to today has been built.
Vennela Damarla: 7:50
That's a really insightful journey. Dr. Yohane, I appreciate how you have detailed that. I mean, a lot of people are not aware of the environmental factors are causing a lot of issues. People mostly focus on occupational exposures, but they neglect the environmental factors. So it's really insightful to know how environmental factors can influence a lot of health conditions. So what are the most common environmental factors that could lead to prenatal health conditions?
Dr. Yohane Phiri: 8:20
Thank you so much for that wonderful question. Vennela, drawing from my own experience and from my own research, the most notable factors that we have explored and I have got scientific evidence or scientific data on, include air pollution. So exposure to air pollutants, such as particulate matter of less than 2.5 micro diameter, nitrogen dioxide, sulfur dioxide, and many other these have been linked to prenatal outcomes. A number of studies, including some that I have done in the US and also that I did in Taiwan, they have provided evidence that factors like pretend birth, low birth weight, status and developmental delays in the neonates or in the offsprings of parents, or in the children that are born from mothers associated with air pollution and air pollution can affect a number of factors, including the fetal growth, the blend by brain development, and this may lead to long term health most of the time we ignore environmental exposures or air pollution as something which is very small, but Most of the effects of air pollution. As far as there are those that we call acute and immediate effects, there are also those that we call a long term effects. We may not be able to know that preterm death, for example, a low birthweight baby was born just because of exposure to air pollutants. Points another interesting thing in countries, I'll give this a specific example, like in countries like Taiwan, where the region is very hot and it's very humid, indoor air quality plays a significant role. So the number of issues, for example, allergens in indoors, indoor environment, in terms of ventilation, in terms of issues with how many times do you clean your household? All these factors are also a significant environmental exposure that could lead to a number of outcomes associated with prenatal health, again, in a modern world whereby we use a number of chemical exposures, also a very, very important thing. Of recent you see that, due to improved scientific findings, a number of companies that produce chemicals, they are enforced, or they are given a mandate to make sure that they provide what we call a safety data sheet for every chemical. This is to make sure that us as consumers, before we use these chemicals, we should know what are the dangers of its exposure. It is important to know that sometime there are a number of exposures of chemicals that have got negative impact. For example, when I was working in a project in Taiwan where we did find that some pest sites that are used to specifically in summer to control the number of, let's say bugs or house flies indoors, were associated with elevated levels of development of asthma in children that were under five. Remember, children are the most at risk from developing such type of conditions when they live in an environment, an indo environment, where there are a number of there's a combination, or there's an integration of a number of mental exposures, so chemicals specifically are another important element. And in most recent years now, like when I've come to the US, I've worked on projects that are focusing on old go systematic racism. Now this goes to socio economic factors. You should understand that there are communities out there that are exposed to environmental factors more because of where they are located or they are based. There is evidence that people from poor socioeconomic background are more likely to be exposed to a number of environmental factors that I did mention of a on like air pollution, they will have poor indoor air quality because they live in dilapidated houses. There's a higher level of into allergens and etc. And one interesting thing is we also have a environmental wildlife, for example, noise, environmental noise, this often keeps to be ignored. It is very interesting that in countries like the US, we have the power we can regulate the amount of noise we are exposed to in our living environment by calling of authorities to enforce these laws. But I come from a developing country whereby most of these wars, they may be there, but they are not enforced, and the number of studies, or the number of scientific research that has been done to explore some of these variables and association with perinatal outcomes has not been thoroughly been established. So the chance that I have here to work on understanding some of these environmental exposures as also with prenatal outcomes, I think it's one of those experiences that are always cherished. So we know there's an impact to do with climate change. Just few days ago, we had a tornado in Buffalo. This is something that has never happened before. Buffalo has never expressed a tornado. So what are some of the impact of these changes in the climate that will impact the NATO outcomes? This may not be in the short term effect, but it could come later on in life with aggregated with other environmental exposures that were exposed daily living environment so, so in short, that's what I think.
Vennela Damarla: 14:31
Well, the climate change is another big topic, though. So Dr. Yohane, you have mentioned about the environmental exposures, such as air pollution, prenatal exposure, socio economic factors, noise pollution, they influence the birth outcome and childhood development. So how do you think these factors influence all those outcomes and development in child?
Dr. Yohane Phiri: 14:54
Remember that environmental exposures play a significant role in a number of outcomes. Not only prenatal outcomes, but when you low birth outcomes or child development, there is a number of ways or mechanisms that these developmental exposures could influence such type of outcomes. For example, pollutants, like air pollution, has been linked to a number of outcomes, and air pollutants can affect fetal development by posing the placenta barrier and leading to a number of what we call inflammation and oxidative stress. Inflammation and oxidative stress, this will end up having an impact on the way the fetus is developing while still in the womb of the mother. This is even before they have come out. So air pollution has that ability to affect the development stages of the fetus while still in the home. A number of our projects that I'm doing now, I've worked on a paper that we examined a neonatal intensive care admission in the US, and we found that of the national data that we use, that's the best certificates data in the US, linked with a number of environmental air pollution exposure we found that about 8.1% of children that are born in the US that are admitted in senior intensive care units, and these are because of a number of issues. And in this research, we try to explore like, what are some of those in terms of environmental exposures? And we're especially focusing on air pollution. And we found there is that significant association with air pollution exposure a month before birth, neonatal health outcomes such as preterm birth and low birth weight. So as I'm saying, We, as far as we cannot trace that actual causal Association, but we are able to think of what, what are some of these factors that are associated with infant development or influences on the birth outcomes in terms of household and outdoor environmental exposures. So these often, like, for example, allergens, they exacerbates respiratory conditions such as asthma in children, and sometimes poor indoor air quality, which may be characterized by higher indoor levels of air pollutants may be associated the development of a number of allergic diseases, but also respiratory issues in children. Remember, when babies are born, their development process was in the mother's womb, then coming out. They need to develop skills to be able to cope up with the outside development and if we have got a number of environmental potents that are being exposed to the environmental potents who tend to affect the natural acclimatization process to be able to breathe well and to grow and remember, they did not have that sufficient immunity at birth. So all that exposure, if you've got a number of these developmental exposures in our living environment, we end up affecting the development the child and the number of early life living environmental exposures that we could be talking of. But in brief, they have an intermediate effect on the development. That's both when the infants are still in the mother's womb, but also when they have come out. So air pollution can affect or environmental exposures can affect both of these stages, and that's where the danger is. Thank you,
Vennela Damarla: 18:36
Well you have explained how indoor air pollution was linked to acute respiratory infection in children under five in your study. So were there any specific pollutant that were found to have the most significant impact?
Dr. Yohane Phiri: 18:50
Thank you. I think in this case, now you are referring to a project that I did in Taiwan, the long examination across prenatal and postnatal health in Taiwan. Yes, there are a number of important factors that we focused on, specifically in terms of indoor air quality and also the ambient air pollution. So we did find that within the household development there were a number of factors that played a significant role. For example, purchase of new furniture was linked to higher instances of respiratory issues. This is likely due to when we buy new furniture. Often, they are coated with chemicals that will probably that for decorative purposes. Some are for the protection of the furniture, and these chemicals produce higher levels of for example, VOCs. These VOCs have an ability to enter into our systems, and in children, such has been associated with elevated levels of presenting with a number of allergic outcomes. For example, as. Ma and also rhinitis. Additionally, for that, in that project, you know, as I already indicated before, Taiwan is a humid country, and also it is kind of hot. So because of this, in houses which have got poor ventilation, you find that you have modes that will grow in the households, and we did find in one of our studies that we did in Taiwan that most smell in the children bedroom were associated with the higher risk of respiratory infections, indicating that the presence of mold not only makes our living environment and comfortable, but also as the power to produce what cause pores and allergens in the air. And these allergens in the air, if in health, will result into poor respirator outcomes and a number of other atopic diseases. So amongst the specific potent we did notice also that allergen levels in the children's bedroom, that's like dust mites, had a considerable impact on health. Our habits. Cleaning habits are really very important, because if we don't clean our living garments that frequently, we leave surfaces that will end up accumulating allergens and dust mites, we may end up developing a number of outcomes. So I think, in essence, my study simply underscored the importance of at least maintaining a clean environment, a well ventilated home that's to minimize indoor airports, which in turn may help to reduce the risk of acute respiratory infections, specifically in young children.
Vennela Damarla: 21:50
So Dr. Yohane, do you think the combined effect of indoor air pollution as well as the smoking habits of family members are associated with higher rates of acute respiratory infection symptoms in rural children.
Dr. Yohane Phiri: 22:06
So smoking habits of family members have been proven to be strong, associated with higher rates of acute respiratory infection when you smoke that Smoke does not only affect you, but it is more hazardous to people that don't smoke. In modern science, we have environmental tobacco smoke. We also have what we call secondary smoking. These are more hazardous than primarily smoking. And for environment tobacco smoke, you find that after you've smoked some of the particles of the smoke will tend to remain attached to surfaces within your environment. So if you're a parent that smokes lives in a rural area or lives but your economically poor background, it is like you're tripping the levels of exposure, because, as I already indicated earlier on, socio economic status is one of the determinant of health. So imagine you're living in an economically disadvantaged community. These details are probably you've got poor access to water, your living environment are already not good. You've got exposure to a number of allergies because you don't clean or because of inability to take care of some of the roles that you have or responsibilities you have. You expose young children, for example, in your living environment, to a number of exposures, adding smoking on, it simply worsens the condition. So the other issues to do with social economic are disadvantaged, you find that their houses probably are not well inflated, and exposure to pollutants in environments that are not well inflated results into a number of heavy outcomes. So the interaction of social demographic factors such as low socio economic status and limited access to health care and education. Disparities, this indeed further complicate the situation. And remember, if you live in a disadvantage community, you are exposing your household to a number of environmental exposures already, and if you smoke, it means you're worsening the condition. Yes, combination of these really worsens outcomes, that's both prenatal outcomes, but also infant health outcomes. So in brief, I think that's what I would say.
Vennela Damarla: 24:38
As a dentist, I know how smoking can drastically affect a person's health, and second hand smoking is something that actually affects more than the person being smoked. So yeah, the smoking habits are definitely are associated with higher rates of acute respiratory infections in children. So there is an article that's. says, the presence of pets, potted plants or living near parks or roads is associated with indoor microbial levels. How do you think these factors influence the indoor environmental quality?
Dr. Yohane Phiri: 25:12
That's a great question, Vennela. So one of the papers that has explored indoor air quality that's endomicrobial and allergen levels association with a number of environmental factors, is a project that I did. I know there are other projects that have been published and have been shared in the academic circles, but in my in our project, we did realize that we did find that having pets and potted plants and also living near parks or roads has got a significant influence on endomicrobial allergy levels and the overall environmental quality of value of your household. So pets, for example, if you have a pet, we often go out with pets, take walks outside, and these have got a direct contact with a number of surfaces, which have got also microbes and pets in so doing, when we bring them into our homes, they may come in with what we call microbes. This may include bacteria and fungi from the outdoor So while some of these microbes, yes, they may be beneficial, others may be might contribute to increase in Indo allergens. And remember, exposure to indo allergens, such as house dust mites, etc, may end up resulting into a number of outcomes. And since my research focuses so much on children and pregnant women's health, there have been studies that are have shown that households that have pets were more likely to have their children with poor respiratory conditions. I know there are some that have proven otherwise, but in a paper that I did, we did find that a household pets, having a pet in a household was more associated with poor respiratory outcomes in children. Potted plants are another important household thing or exposure that is discussed amongst scientists, especially those that focus on government exposures, so household poly plants may have both positive and negative effects, so they can improve air quality. You know, we talk of the photosynthetic processes, they will be able to clean our environment if it has higher levels of carbon dioxide, because we understand our survivors humans is totally dependent on plants. But at the same time, they also may provide large surface areas for harboring moths, because, you know, the leaf surfaces provide a very nice environment for moths to grow on. So if it is advisable to clean these into potted plants frequently and make sure we check them if they do not have any moths that are growing on them, because if there are these moths that can grow on them, these moths can release spores into the air, and those moths have a potential to exacerbate origins and also respiratory conditions. Living near parks, it is very important to live near Park because parks provide an environment whereby we could take a walk and kind of refresh ourselves, but we should remember that proximity to parks can also have a disadvantage. Remember, parks have got different types of plants that are grown there. There are some plants that produce allergens they produce and and this is, suppose, the diversity of these or these airborne microbes that come from those plants may enter, probably our homes, if we have got a home close to a park, and we may get exposed. Remember, each and every human being have got different levels of atopy. That's the way they react to different types of environmental exposures. So leading to parks can have can quite a double edged saw in that we may have some microbes that you get exposed to in parks that you walk, that are beneficial for our everyday, everyday life, but also some that may trigger a number of heavy outcomes. So when we come comes to population that I focus on as perinatal pediatric health for children and for pregnant women, often times, exposure to such type of environments may lead to poor healthier. Outcomes, and because, if you are living close to these parks, you may end up getting a higher levels of specific types of probably alleges, or, let's say, spores or pollen. And these will tend to exert to worsen the conditions, some of the conditions that come due to pregnancy. You know, I always call or in science, we call pregnancy and inflammatory stage, whereby you've got a number of changes that are ongoing in you, and this will have an effect on your immune system. Your immune system already gets weaker because of the pregnancy stage. So exposure to more of these new allergens, or more spores or more pollen, due to proximity to parts, may result in poor, healthier outcomes. So as far, it is a double EXO I would advise during this time, exposure to such type of environments could really be reduced so that we avoid such type of poor heavy outcomes.
Vennela Damarla: 31:10
Well, this is something new I got to learn today. So imagine having a pet and then just to know that the indoor microbial levels are increasing just because of the pets. I mean, it's sad to know that, because I have always wanted a dog in my home. So moving on to the next question, how do socio economic factors and prenatal mental health influence the relationship between environmental exposures and child health outcomes?
Dr. Yohane Phiri: 31:39
So thank you so much for that, for that question. Vennela, let me start this question. Say, having a pet is not a problem, just going back to your comment, but it is important to be informed of some of the exposures that we may get from our pets. We take care of our pets, at least take them to the to the to the vets for checkup. You need to clean them. You need to have places where you can keep them, and within our environment, if you're taking a dog for a walk, I've seen a number of people that will probably have a specific designed covers for the feet, a number of ways to make sure that when the dog comes in an indoor environment does not bring does not bring in a number of some of these plausible environmental potents that we're talking about. Now let's go back to the question that I asked me, and you talking of this psychosocial influences of probably parental health or mental health and children health. So we talked a lot about the physical environment, but parental mental health is also one of the most important issues, one of the most important factor that is associated with child health. So when parents experience stress and desirable depression, this may have an effect on how they manage their home environment. That's the first thing, not only that, but depression, anxiety and also stress, may have an impact on how the immune system works. So for example, a pregnant woman who is depressed or has got anxiety or have got, has got stress, they are too likely, possible outcomes that will impact how they clean their home environment, leading to increased indoor allergen levels. It may affect their cleaning habits that may result into household environmental factors. There are some that will even go to the extent of probably nudging in risk behavior, such as drinking and smoking and all these will have an impact on the unborn baby. Depression, stress and anxiety has gone an influence on our immune system and how it works. If you are depressed, if you are stressed, you will be likely to end up not having a balanced diet. You are more likely probably not to eat if you are pregnant, that's even very bad for the devolving child. So these are some of the factors that when we are exploring the association between environmental exposures and neonatal heavy outcomes or prenatal health, we also try to understand that such psychosocial factors may be mediators of our association. Between environmental exposures and health. I worked on a project in Taiwan, and in that project, we're trying to look at the outcomes allergic rhinitis, conjunctivitis and also asthma. And we wanted to see whether parental mental health status, that's depression and anxiety were associated with the likelihood of their offsprings or their children developing asthma, conjunctivitis, rhinitis and also eczema. And we did find that a number of kids in that study whose parents had depression had three to four times a higher likelihood of developing eczema. So it tells you this parental mental health or psychosocial factors, I significant factor that may affect a child health, that's both when they still in the developmental stages during pregnancy, but also if they are already born and they are growing up, because, as I already indicated, psychosocial factors are really significant in Determining what could behavior of the people that have watched stress, depression or, let's say, anxiety. So the combination of socioeconomic challenges and parental mental health simply can amplify the negative effects of your mental exposures on children's health. So and this highlights the need for a whole for holistic approaches in addressing child health. So when you addressing child health, you should also make sure that we take into account not only their physical environment, as I do focus on environmental exposures, but we also try to see whether their mental health or emotional well being or emotional being with the entire family is also at play in some of the outcomes that we assess.
Vennela Damarla: 37:07
Thank you, Dr. Yohane for breaking down it so clearly. And I also believe that depression is one of the most suppressing issues worldwide. Moving on to our next question, how can your research finding be used to develop public health strategies and target innovations which are more effective.
Dr. Yohane Phiri: 37:27
I'm just one of the people that probably focuses on environmental exposures and in number of different types of outcomes, interdisciplinary research helps in addressing a number of these factors. But in terms of policy research and practical recommendations, I think the research that I'm doing now provides valuable insights into a number of factors which can significantly enhance public health strategies and intervention specifically for all the work that I have done in epidemiology and environmental health highlights a number of factors. First of all, it leaves us to with the responsibility to identify at risk populations. So most of the research that I've done has been pointed like which populations are most vulnerable to specific research. For instance, in my studies, I did review that there were certain communities in probably in Taiwan, that way more plausible, more prone to environmental hazards. And therefore, what should we do in order to avoid that, but also in terms of informing policy development by providing this evidence that I've just spoken of, it is we provide the link that exists between environmental factors and heavy outcomes, and These findings can inform policy makers about the need for regulations or changes in environmental standards. For example, some of my research has found association between Neonatal Intensive Care Unit emissions and also air pollution. We policy makers could try to work with these findings and see how they would manage to control both stringent rules and regressions in the management or regulation of air quality standards, but also we talk of designing interventions that are targeted to specific populations that could also work. We were talking of he has in prevention programs. So as I already said, some of the environmental exposure that I specific around specific communities, they wouldn't need a whole city or a whole region to change. Change their policies. They deal with issues to do with hygiene, keeping our environments clean. My research provides the basis for knowing that probably, if we target this population and probably gave them health education on issues to do with keeping their household clean, ensuring that they have got proper ventilation. A number of factors affect associated with the environmental living environment, we could probably change the direction of some of the outcomes that I have I've spoken about
Vennela Damarla: 40:40
Those are actually the excellent strategies in order to target the interventions more effectively. So what are some actionable recommendation for policy makers to reduce the impact of environmental pollutants on prenatal and pediatric health?
Dr. Yohane Phiri: 40:56
Thank you so much. I think one of the most interesting thing is that being someone has started in a number of countries and seeing how in different countries, like duration, dealing with air quality issue to do with environmental exposure works, I should applaud the US for taking a very Good initiative in making sure that there is a controlled way of making sure that the have got they have strengthened air quality regulations, so one of the findings or recommendations around to give is to further strengthen these Air Quality regressions of interest in the US. I think from the literature that I've read, there has been a significant improvement in terms of levels of air pollutants. There's also issues to do with enhanced monitorings, so there's to be increased funding for even mental health available systems to track, probably pollution levels and the impact on vulnerable populations. So I understand as far as the number of tools that have been used, number of regulations draw to regulate air pollution, one of the important factors is also to focus on promoting multiple green spaces. So in most of our urban planning, most of the poor air quality occurs, largely in cities. This is because cities have got probably a number of high high levels of traffic, and also like production factories, etc. So investing in promoting green spaces could also really help in reducing these environmental exposures. But also we have to focus on strategies that focus on reducing exposure to indoor air pollution, or indoor air pollutants, so families can immunize this. This goes to individual families by making sure that they use methods of cleaning indoor air, potions. They avoid smoking indoors. They choose non toxic cleaning products, and also making sure that they regularly make sure they live in environmental Well, inflated and also most importantly is out say, promotion of a healthy lifestyle. I think part of our immune system, as far as environmental exposures are concerned, most of our part of our health system also depends on our lifestyle, so encouraging practices such as consuming organic produce when possible, reducing the use of plastics to minimize exposures to harm of chemicals, issues to do with making sure that our lifestyle is health frequent exercise, this would also help in probably reducing a number of the effects of mental exposures that affect pregnant health. Think that's all I would say. In summary,
Vennela Damarla: 44:14
I would completely agree with you. Dr. Yohane, lifestyle changes and staying hygiene are the most important things in order to mitigate the most of the environmental risk. So how can families and healthcare providers use the findings from your research to make informed decisions in eliminating the environmental risks?
Dr. Yohane Phiri: 44:36
So when talk of healthcare providers think we're looking at now integration of environmental health into routine care, so Heather providers to basically focus on routinely assessing environmental exposures in prenatal and pediatric healthy settings. This includes about both the home and also the Community Environmental Research and provide. Guidance on how this could be mitigated. Uh, secondly, I think we could focus on advocating for regular health screening. So we have to promote regular screening for conditions that may worsen, that may be worsened by environmental exposures, such as asthma, allergies and developmental disorders, if these are screened regularly and we notice that there are some precursors to their currency, we would start to figure out, probably it could be because of their living environment of that specific community end up being addressed, but also we have to educate and empower our communities. So we have to provide our committees with up to date information on how environmental potents can affect health and offer practical advice on reducing exposures. One of interesting factors that in the developed country, like the US, I've noticed that we are able to find information of, for example, air pod levels that are in Buffalo because we've put a number of monitoring stations that are around us. This goes back to communities. It is our responsibility to stay informed of a number of exposures that we're exposed to. As far as the government is taking part in ensuring that they regulate and control the levels of air pollutants, but we also have to stay informed some of these changes in local level air pollution is not directly impacted affected by the activities of our local governments, etc. These are some of these our local, localized or personal air pollution exposure are affected by the activity that we do within our living environments. So we should be aware of the changes that are having an environment and how these may affect the levels of environmental process that we are exposed to in so doing, who help to prevent exposure to higher levels of mental pollutants that may impact our health.
Vennela Damarla: 47:16
Thank you. Dr. Yohane, what final advice would you give to your listeners about protecting their families from environmental hazards?
Dr. Yohane Phiri: 47:25
Thank you so much for this opportunity. First of all, I think to me, all I would say is, let's stay informed, stay educated. Let's educate ourselves about some of the common developmental hazards in your area, or whether they are air or water quality issues or exposure to harm, chemicals or risks from climate change. Let's always stay informed. Understand this research. Understanding these risks may help us to take proactive measures, for example, reporting if we see that within our environment there's a leakage which is probably causing chemical exposure, or if there's a fire which is resulting into higher levels of pollutants from burning or from fire, we could report this, and our local government probably will take responsibility in trying to avert or correct some of these effects. And another thing is to, let's ensure that we improve our indoor air quality so regularly. Check and maintain if you've got air filters at home, maintain them if you smoke, which I would encourage you to do. As an environmental epidemiologist, I would, at all costs, advise you to avoid smoking, but if you do, make sure that you avoid smoking in indoor environment and also for cleaning, make sure that when you buy a cleaning product, reach the material safety data sheets that are always some of them are always attached on the bottles, or you've got a link on the bottles or the packaging of the chemicals, read about them and see whether It's non toxic and will have no impact if you are exposed to them. And also importantly, let's ensure that our houses are well inflated and make sure that we continue to promote personal hygiene and our living government hygiene, because these are also significant precursors to higher levels of indoor environmental potents, and also it means that's a precursor to indoor air quality. If our indoor environments are not well cleaned, we've got higher levels of air pollutants, poor indoor air quality, and finally, health. Habits, let's encourage each other to have heavy habits such as washing hands, regularly, practicing food safety hygiene and food safety handling, but also making sure that we eat where we can eat organic food or we can eat food that has not been processed with a number of chemicals, because that would also improve our health. So in short, I think these are the most important recommendations that I would share with you. Thank you so much.
Vennela Damarla: 50:34
Thank you so much for your time. Dr. Yohane, your points have sparked a lot of thoughts. Stay tuned for another episode on Buffalo HealthCast. Thank you.
In this episode of Buffalo HealthCast, we dive into the world of long COVID with two distinguished experts, Dr. Sanjay Sethi and Dr. Jennifer Abeles.
Join us as we discuss the challenges faced by patients and healthcare providers, and uncover the importance of research and studies being conducted at the University at Buffalo. Whether you're a healthcare professional, a patient, or simply interested in learning more about long COVID, this episode offers valuable insights and practical advice.
Tune in for an engaging and informative conversation that sheds light on the critical aspects of long COVID, and the efforts being made to advance our knowledge.
Nada Fox: 0:06
Welcome to the buffalo health cast the official podcast of the University of Buffalo School of Public Health and Health Professions. Today, we're exploring long COVID with two of the experts. Dr. Sanjay Sethi, Deputy Director of University at Buffalo's Clinical and Translational Science Institute and Dr. Jennifer Abeles co director for long COVID Recovery Center, internal and pediatric medicine at the University of Buffalo Jacobs School of Medicine and biomedical science, whether you're a healthcare professional, affected by long COVID, or just curious, this episode is full of valuable insights, sit back, relax and join us on this podcast. Let's get started. Thank you both so much for joining us today. Before we get into it, can we do an introduction into long COVID For those who are not real familiar, what exactly is long COVID.
Dr Jennifer Abeles: 1:01
So long COVID are symptoms that occur after having had COVID occur about three months after having the infection that can't be explained by any other underlying medical issues.
Dr Sanjay Sethi: 1:16
So essentially, most in most cases, you know, the symptoms will disappear. And some they persist, and some actually new symptoms appear. So it's, you know, it's not just that the COVID never recovers. I mean, that's a common scenario, but also sometimes it might get better, and then they start having new problems, which again, as revealed, as Dr Abeles said, it can't explain otherwise.
Nada Fox: 1:37
How common is long, long COVID among individuals who
Dr Jennifer Abeles: 1:37
Documentation right now is about 6% of people who have COVID will develop long COVID, that number has changed over time, it's been as high as I believe factor set the 11%. And I've seen as low as 3%. So it seems to be variable at times, but 6% is what I've seen published most recently, have had COVID 19.
Dr Sanjay Sethi: 1:45
Yeah. And just to add to that, you know, yeah, it is extremely variable and varied. I would add to it. We've all right. I guess it also, to some extent depends on when and how you look for it. So earlier, if you look at people at three to six months after they had the acute COVID, seen anxiety and depression. I mean, that could be because of you're going to have a larger proportion if you look at six months to a year out. So people do recover. And then you know, the numbers are, are less than so about 6%, I think is a really good estimate. Today. the COVID, long COVID Or could be a part of the long COVID. You
Nada Fox: 2:28
significant portion of the population. Wow. What are the most common symptoms associated with long COVID.
Dr Jennifer Abeles: 2:35
The most common ones we hear about are fatigue, fatigue, both at rest fatigue with exertion. Brain fog, is another one people talk about confusion, memory loss, see a fair amount of that. And what is interesting is that some shortness of breath, some pulmonary symptoms, cough, some sleep disturbance. We've seen other things, we've seen some cardiac issues, most commonly called pops where they have different studies done in different parts of the country, really high heart rates, and they feel like they're going to pass out or they actually do pass out some of the more common ones. But there are a lot of symptoms of long COVID that we get complaints about or people describe. including ours, they all kind of show the same pattern. So
Nada Fox: 3:14
How soon after the initial infection do symptoms of obviously it's you know, there's something consistent about the patterns of the disease. Of course, it's mainly a respiratory disease when it's acute. But long COVID long COVID typically appear like how do we start distinguishing initial COVID infection versus long COVID infection? Interestingly, is much more of what you would think is more of
Dr Jennifer Abeles: 4:12
I think as Dr. Sophy mentioned, some people will have COVID They'll get better from the infection and continue to have some symptoms. Some people recover completely from long from COVID and then develop new symptoms about three a neurological problem with the fatigue, the brain fog, you months after two to three months after having had COVID. They completely recover and then develop symptoms. So it's variable. When the symptoms start for each individual know, the difficulty concentrating, and also the patient and what it is some people will develop new symptoms like the brain fog, the fatigue, some people will get worsening of chronic medical issues they already had before having COVID autonomic dysfunction. So it's very individualized. You can't say all people with long COVID present this way.
Dr Sanjay Sethi: 4:57
You know, I think we have to be a problem, because the symptoms are kind of nonspecific. So, you know, fatigue is can happen because of other reasons, you can have difficulty concentrating because of other reasons. So we always have to make sure that not something else is not going on. So, you know, people shouldn't just assume I had COVID, and I'm having this problem, this is long COVID, we see that quite often. And then we try to dispel that notion because and also look for other reasons, because the last thing you want to do is miss something which is treatable and and related to their medical problems, or their medical problems, rather than the COVID. itself.
Nada Fox: 5:33
Are there any specific like criteria or tests that we use to diagnose long COVID?
Dr Jennifer Abeles: 5:39
we wish there were specific tests used to diagnose long COVID, a lot of the testing that's done, I mean, we see patients that have had a huge amount of testing, I think that's one of the biggest frustrations, they have all sorts of bloodwork, it doesn't really show very much. That's abnormal, they have all sorts of cardiac workups, that are relatively normal, they have all sorts of imaging and diagnostic testing, and it's normal. And I think that's one of the biggest frustrations is people have a lot of testing. And in the end, the testing looks normal, but they still have these very distinct symptoms that we attribute to long COVID.
Dr Sanjay Sethi: 6:18
So there's no specific diagnostic tests, most of these are what we call rollout, you're looking for other things. And in any other part of the reason we don't have a specific diagnostic test is because you don't understand it fully and you know, and maybe different ways by which people get along COVID. So I think that's definitely a challenge we have,
Nada Fox: 6:40
yeah, I saw on the UB long COVID site, there is a registered registry survey form that people can complete. Are you hoping that that'll kind of lead to more diagnostics, criteria for it,
Dr Jennifer Abeles: 7:00
we actually started our long COVID work. Through the survey, we wanted to evaluate the individuals of the Western New York area to see who was being affected by long COVID. So before we ever started the recovery center, that was a research project, we started, where people can go online and still are going online and filling out the survey and giving us information about themselves when they had COVID, how many times they've had COVID, how bad their COVID was, treatments, they've gotten, you know, their medical history, it's very, it's a very comprehensive survey. So they start that way. And then based on doing the survey, they can be evaluated at the recovery center if they choose to. That's where we provide the treatment component of the long COVID.
Dr Sanjay Sethi: 7:49
And you know, of course, we we would like to develop diagnostic tests. But right now it's more of understanding the spectrum and and then introducing these people into other research studies, which hopefully can help us define the disease better. This is becoming clear that the standard diagnostic testing is not going to give us a test that's going to work. So I think we will, as we understand it better. Hopefully, there are other tests that are
Nada Fox: 8:14
Are certain populations more at risk for developed, which are more specific, you know, and somehow can diagnose the problem better. developing long COVID.
Dr Jennifer Abeles: 8:26
We have not found that yet that there's a certain population, we do know that certain groups are more engaged in the long COVID survey and Recovery Center. And we're trying to actually enhance the availability and the knowledge to all community members of the Western New York area. So I have not seen that certain individuals groups are more likely to get long COVID Just more people are more likely to look for support and treatment for long COVID.
Dr Sanjay Sethi: 9:03
Right. I mean, there's a suggestion that the literature and women get it more frequently than men, there is that suggestion in the literature that's not like, you know, the, say the higher incidence and women by the looks of it. And, and the second thing or maybe that, and again, that's one of anecdotal observations that people will take preexisting, autoimmune kind of conditions, those people seem to be somewhat more predisposed to getting the symptoms worse or new develop new problems after after COVID. But that is somewhat anecdotal, and yet completely healthy people without any problems can also develop long COVID.
Nada Fox: 9:42
So we're still learning in real time about that
Dr Jennifer Abeles: 9:45
every day.
Dr Sanjay Sethi: 9:47
Absolutely. And I'm building the bridge as we walk on it, you know, trying to understand and manage it at the same time.
Nada Fox: 9:54
That sounds like a very simple task. What impact is long COVID have on the daily lives and functioning of those affected.
Dr Jennifer Abeles: 10:04
I mean, the effects for some individuals is profound, we have seen numerous people who are no longer able to do their jobs. I mean, that is not uncommon for people to need support, and to apply for disability to just be so overwhelmed by the symptoms, you know, when you can't do your activities of daily living without getting exhausting. So there's no way that you can perform your job the way you did before you have long COVID. Even people who don't have support from family, I mean, it's it's profound, how affected some people are their entire world turns upside down. And this is, I think one of the hardest things is you take people who were relatively healthy before having COVID. And you they go through the COVID infection, and they end up with long COVID. And they can't do anything the way they did it before. And I think that's one of the hardest realities, to work with them to kind of learn the new norm for them, and how they can live in that. And that's where a lot of the anxiety and depression comes from, because it's really relatively sudden.
Dr Sanjay Sethi: 11:15
Yeah, absolutely. I mean, again, there's a spectrum, like the spectrum of the disease is a spectrum of impact. And, as was mentioned, there are some severely impacted others, you know, unless impacted, but still, it's a problem. I mean, it could be something like, you know, that some people never recover their sense of smell and taste, which may not seem, which becomes a big deal if it's with you for a very long time. So things like those. And so, Spectrum exists, and, and, you know, we just have to be cognizant of that.
Nada Fox: 11:50
That sounds heartbreaking as somebody that loves food. And I consider myself a foodie, you know, the idea of not being able to smell or taste that would break my heart.
Dr Sanjay Sethi: 11:59
I know.
Nada Fox: 12:00
Oh, especially now that we got to James Beard nominated restaurants in Buffalo heartbreak. Alright. So what are some of the current theories about why long COVID occurs?
Dr Jennifer Abeles: 12:13
Oh, that's a loaded question. Yeah, let you take that one to start.
Dr Sanjay Sethi: 12:19
Yeah. So there are several theories. First of all, you know, after viral infections, other viral infections, people also use to develop these kind of problems, you know, a small proportion. So it's not, it's kind of known that this can happen after any kind of virus infection, but because we have so many people with COVID, and because the infection was so, so prevalent, and so, so much more impactful, we've seen you no longer with suddenly has become a big part of a conversation. So the thinking is a bit again, because you don't know it, there are several theories. And it could be that not necessarily one pathway is the one that's causing it. So it could be like, one of them is like, Is it some kind of an immune dysregulation, so your immunity gets out of whack because of the infection. And because of that, you know, it doesn't come back to where it's supposed to be and then starts impinging or attacking other organs of the body. So some some form of autoimmunity. That's one of the speculations or theories. The second is some people, you know, there's some evidence of persistent viral infection, that somehow the viral the virus persists in parts of the body and is driving the infection. So that's driving the symptoms. And that's been thought about things like changing the microbiome, you know, there is some nice data showing that changes in the gut microbiome could also be can be described in these people. And that could be also in some way implicated in the development of the problems. So I think it's going to be multifactorial. And there may be different mechanisms, and not necessarily just one, but those are some of the current theories. Jenny, you want to add to those? I'm trying to think there are others out there too.
Dr Jennifer Abeles: 14:04
That's more recently I've been reading about where there's a breakdown in blood brain barrier. So all right, usually, things in the blood cannot get into the brain, in human and what they're assessing that there is a breakdown, and so that they're getting into the brain matter, and that's affecting some of the neurologic, that we see. That's one of the newest ones I've just read about.
Dr Sanjay Sethi: 14:30
And I would add to it chronic inflammation in different parts of the body, though. It's interesting when we do the standard markers of inflammation there many of them like things like ESR and CRP, they're often not raised, but that doesn't mean that they there is not tissue inflammation that that is driving it. So that's another, you know, tied in with the immune function and dysfunction. That's another hypothesis behind what's driving long COVID
Nada Fox: 14:55
What treatment options are currently available for those suffering from long COVID Is there any treatment?
Dr Jennifer Abeles: 15:02
I mean, it's slowly coming out. Some of the things that we have seen, and we are starting to use here at the Recovery Center are related to like chronic fatigue syndrome, that treatment where you do physical therapy exercise, but in a very distinct method, where you're exercising in a very slow controlled manner to not overwhelm the individual, because too much exercise actually causes harm for some of these people. So you really have to be very careful in the type of physical therapy that you prescribe, providing the social support for these individuals. So they feel that they have that emotional and component, and then occupational therapy, or relaunching how they think about their daily life, things that they do that occupy their daily life, and changing their perception on how to engage in those things in a meaningful way, but in an adaptive way that they can handle those stresses, there's no particular medication that I'm aware of that's been recommended at this point.
Dr Sanjay Sethi: 16:08
So yeah, you know, several things have been tried. But they're all in kind of clinical trials stage, many time things are being repurposed, or people are trying, for example, giving the antivirals to see if that makes a difference. A study we may launch soon as giving IV immunoglobulin to modify the immune system. So then there are many other studies going on with with other kind of treatments that are used for not for specified for COVID. But were being used for other things. And now they're being tried over here. I think, at this point, if one is has the problem, and there are trials that are open and available, that's the best way to be, you know, get the opportunity to get treated, because unfortunately, as like everything else that was done a lot of you know, unproven treatments out there that people are offering without any evidence, which could even actually make things worse. So. So I think, given the fact that
Nada Fox: 18:01
Well, based on both of your experience with patients, there is no specific treatment, I think getting involved in what are some of the biggest challenges they have in managing their long COVID?
Dr Jennifer Abeles: 18:12
I think one of the biggest challenges for research studies where there are things being tried is the best the individual patient is really getting the providers that they see family members to understand that they have a true illness. I option. But that all the attention to it, I'm I think think that's a huge frustration when we get patients into the recovery center. It's one of the first times they hear, we hear we're pretty convinced that in the next, you know, me take two you, we know you're suffering, and the patient's frustration in saying I have told my primary I told my specialists, and they three years that we will at least develop treatments for just, you know, think it's made up, they don't think it's real, and that they don't patients don't feel supported by their some of them. And As Jenny mentioned, we're doing family. Because again, you can't say, oh, look, here, I've had a Rehabilitative Services, kind of, but in a very, in a very heart attack, I've had a stroke, the patient looks the same to them. And the patient doesn't feel heard, and they don't feel specific way. And very personalized way. I think that supported. And that's a huge frustration for someone who's really struggling with their health to not feel like other we know, at least, if done properly, will not do any harm. people are hearing them and supporting them in the method that they need.
Dr Sanjay Sethi: 19:08
And, you know, I'm totally agree but also for So I think that's what I would recommend for almost any the providers is difficult for people like us also, it's difficult not being able to have the lack of having a specific, a individual today without reservation, with the caveat diagnostic test and be specific treatment is a challenge. So, that it has to be personalized and and managed by somebody who you know, so that that becomes a challenge in the provider aspect of you. But yeah, patients, you know, I agree, clearly being knows what they're doing. But beyond that, in terms of heard being supported, is important. And I think that would be a good place to start. And also having maintaining hope medications, nothing specific at this point. because a people do improve with time. And be as I said, there is so much going on that it's just a matter of time before we find something that's going to work from it not maybe not all but a good number of people.
Nada Fox: 19:54
So what do you think is crucial for people to understand about long COVID
Dr Jennifer Abeles: 19:58
I think people need to understand that long COVID has affected a lot of people in our community. It's something that we, as medical professionals are actively trying to better understand. So that we can discover proper treatments that will help everybody and support people as we go through these research trials and clinical trials to help people and that people need to know that there is hope that they will get better, we will figure out more with time, we figured out a huge amount of information already just dealing with COVID, and then well on COVID. But we just need more time to work with individuals and as a community of researchers and medical professionals to come together to find the solutions for everybody.
Dr Sanjay Sethi: 20:51
Yeah, very well said. And I would just add, I mean, I always say look at, for example, the HIV epidemic when it came on, we had no hope No, no, no good treatments, didn't really fully understand it, and see where we are today where it's become a chronic, manageable, you know, disease. So I'm hoping that that's what will transpire here. Again, I don't want to people to think that long cord and HIV are similar. They're not. But you know, the concept of when enough attention is paid by physicians and researchers on a certain disease. I think, you know, things happen. And so I really do anticipate that's going to be the case over here. So I think the whole part of it, we definitely want people to maintain that.
Nada Fox: 21:39
All right, well, here at UB, we have the long COVID Recovery Center, which you both are a part of. And you mentioned your multidisciplinary team, I heard you mention physical therapists, occupational therapists, are there any other disciplines that y'all bring in when working there,
Dr Jennifer Abeles: 22:01
we have a social worker here as well, that is working with our individuals who need mental health support, as well as figuring out disability and things of that nature that may be very new to individuals, trying to provide that social support with social worker to help them we do bring in, or we do send our patients to specialists, as indicated by each person's unique physical needs and complaints so that we make sure we're seeing the whole patient,
Nada Fox: 22:33
how does the community access, get access to the long COVID Recovery Center,
Dr Jennifer Abeles: 22:41
the best place is to go online and do the long COVID survey. That is the best entry point you do that. And then Sarah actually looks at all of those results. And then we'll reach out to patients and ask if they want to be at the Recovery Center, and help to facilitate getting them an appointment. And at that point,
Dr Sanjay Sethi: 22:59
right. I mean, that actually is the best way because the survey not only just, you know, provides us a good mix, mix mix helps us to make sure that they meet the, you know, the definition of long COVID but also gives us like a baseline of where they are. And then we in the survey, we actually are now going back to people six months out and 12 months out and every kind of every six months to see where they are going next. So I think really, that to us is the best way to to get involved in the Recovery Center. We're also doing several outreach, you know, outreach activities, especially in the underrepresented communities and in the in the inner city communities to you know, to get them involved because sometimes they don't really have access to all this information as readily as, as others do. So the between the outreach and the survey, those are ways to really get involved.
Nada Fox: 23:59
How can family members and friends and loved ones best support someone who is dealing with long COVID
Dr Jennifer Abeles: 24:05
is like any other medical issue, I think just accepting the patient or the in that family member as they are and just accepting them at their word that I'm sick and being supportive and saying what can I do to help you just like you would do with anybody else who perhaps you can actually see the illness? Just say, Okay, you have long COVID What do you need from me? What can I do to help you? Can I take you to appointments? Can I help you with making meals, things of that? I think that would go a long way to support a person who's suffering in their own way. And the acknowledgement of saying, Okay, I'm here to help you.
Nada Fox: 24:47
Are there any steps that we can take to potentially reduce our risk of developing long COVID
Dr Jennifer Abeles: 24:55
We know that research shows that getting your COVID vaccine It is an important step in preventing individuals from getting a sick with COVID. And it also does prevent people from getting long COVID. So vaccination, continuing with that mindfulness of getting your vaccines as updates come out to protect yourself, especially our older individuals over 65, making sure they're getting their vaccines, if people are sick, being good about being sick and staying away from others, and, you know, protecting our friends and our loved ones by staying home, and we know we should stay home.
Nada Fox: 25:36
Right. And now, again, that is long COVID Recovery Center here at UVI. As a sounds like a valuable, invaluable resource for our community to you know, you have just a small task of you know, the diagnosis and the treatment, the support all of those things. Is there anything that you would recommend for the individuals struggling with long COVID? Like, how, besides reaching out over the survey and anything? Is there any way? How do we get the people suffering with long COVID? The family members that are trying to support these individuals dealing? And how and winking them with you? Is there any other way besides the online survey? Can they send an email? Can they call? Is there anything like that, that they can do,
Dr Jennifer Abeles: 26:24
they can send an email, we do have an email, we use calling again, can be done. But it's I think, very cumbersome, because then it requires a call back and then asking the questions and asking them to do the survey. So they could email but again, doing the survey and at least getting started on that would be the easiest one because again, Sara will reach out to somebody who hasn't finished it, perhaps they got too tired to do that. And they can she can support them and helping them to finish it as well. We have had some individuals who had to be called, and they did the survey online. And Sarah helped arrange that, as well.
Dr Sanjay Sethi: 27:07
And you know, also, I think, people, I mean, if they are having these unexplained symptoms, having the conversation with the primary care physician is important, you know, not to just ignore them, but have a conversation with them. Many times the primary care physicians can at least do a lot of the baseline testing to see make sure that that is not something else, you know, that that has been missed. And, and then and then you know, then going ahead and getting involved with the Recovery Center is the way to go today. And, you know, we're hoping to, you know, actually putting in for a large grant from the quarry to see if we can, we can package this whole rehabilitative approach, tested, and also make it available more widely across Western New York. So the funding proposal is still working on it. So we'll come to know later in the year, whether we did get the support, and that'll actually enable us to do more outreach and treat a larger number of people. So we're hopeful for that. But I think in any case, you know, the there will still be opportunities within the recovery and center. And, and the other thing is to look for research studies, you know, the recent study is going on. And then if you think you meet the criteria get involved. So anyway, we're gonna move this field forward.
Dr Jennifer Abeles: 28:25
And that's one of the nice things if you do the survey, we actually provide a monthly newsletter that goes out to all the individuals who've done the survey, just with up to date information, newest research studies, he was findings, really trying to have that back and forth, and provide individuals with continued to support what's the newest research. And if there's a new research study that's available locally, and they meet the criteria, they will receive an email indicating the information and giving them the choice to participate if they want. So again, the survey does more than just provide us with information. It's a two way street providing information on a monthly basis back to the individuals who've completed the survey as well as the ability to get involved in different research studies that are available locally, that they might choose to be involved with, if they find that that would benefit them.
Nada Fox: 29:19
Going forward would would you like primary care to kind of start referring any suspected like long patients long COVID patients like do you think that would be like a good
Dr Jennifer Abeles: 29:29
I'm like that per se that I do primary avenue. care physicians can do a lot of the beginning workup outside of the long COVID Recovery Center, you know, the basic labs that we run, if there's cardiac symptoms, evaluating that are respiratory symptoms, because again, we don't want to repeat things that have already been done. If an individual comes to us and says I've already been my primary care doctor and they've sent me these other specialists. We will get that information and look at it. We don't want our Uh, you know, recreate the wheel take people's time to do all these things. Again, we're looking to have a collaborative response with the patient and the doctors that they've already seen.
Dr Sanjay Sethi: 30:11
And, you know, finally, I mean, there's no way we can just have the one Recovery Center to take care of all of these individuals. So, so I think, yeah, the plan would be to develop, you know, as as knowledge becomes better as our treatments become better and a diagnosis, you know, we would be, we hope to be in the center of trying to disseminate this information out to the primary care providers, so that they actually get empowered to deal with, you know, a good number of these individuals.
Nada Fox: 30:37
Well, thank you so much for your time today. Is there anything else you'd like to share with our listeners about long COVID that we haven't covered?
Dr Sanjay Sethi: 30:47
I would just say stay tuned as it lots to come.
Dr. Sanjay Sethi, MD
Dr. Jennifer S. Abeles, DO
Elizabeth Bowen, PhD
Associate Professor | School of Social Work
Join us for an enlightening conversation with Elizabeth Bowen, PhD, an expert in addiction recovery and recovery capital. Listen as we discuss the invisible population of persons experiencing homelessness and the unique issues this community faces, trauma informed care, and the need for supportive housing.
Nada Fox 00:00
Greetings, public health enthusiast, and welcome to another episode of the Buffalo HealthCast podcast. My name is Nada Fox, and I'm going to be your host. And I'm beyond thrilled today to have a distinguished guest with us someone whose experience and expertise spans the vast landscape of Social Work and Health Research. Dr. Elizabeth Bowen, thank you for taking the time to speak with us today.
Dr Elizabeth Bowen 00:23
Thanks so much. I'm excited to do this.
Nada Fox 00:26
Can you tell our listeners a little bit about your background and your experience,
Dr Elizabeth Bowen 00:31
Of course, this is a big part of why I do the research that I do. But so my name is Elizabeth Bowen. I'm currently an associate professor in the School of Social Work here at UB. But my background, before I went the research route, my background was in social work practice. So after I got my master's degree, I was working as a social worker in Chicago, and happened to find a job working in supportive housing programs. So these were programs that helped people experiencing homelessness get into stable, affordable housing with supportive services. And a lot of the clients that I worked with had a history of addiction and substance use problems along with other kinds of physical health problems, sometimes mental health issues, lots of trauma, so a lot of co-occurring issues. But in any case, in this work, what I saw was that, it seemed like my clients were getting this message that if they were unable to manage their substance use problems. And if they were not succeeding in recovery, it was kind of their fault. So they had often been in and out of various treatment systems. And they had gotten this message that, you know, if they were motivated, it would work. So if they were struggling in recovery, it was because they didn't want it bad enough, or they weren't motivated. And so people, I heard that from my clients in many different ways over time. And often people internalize this message. And it caused a lot of shame, it caused people to feel bad about themselves when they struggled with recovery. But from my perspective, coming into this, I didn't see it that way. It felt to me like it wasn't that they weren't motivated. It was more that they lacked stable housing, they lacked basic resources, it was just nothing in their life was really set up to be conducive to recovery. And so that felt really unfair to me that they're getting this message that it was their problem that they weren't motivated, rather than looking at the environment and looking at how things could be better set up to support them for recovery, including that really vital thing of having stable housing. So I know that's a long answer. But that's the clinical practice experience that always stuck with me. So then years later, when I decided I was interested in doing research, this was one of the things that remained interesting to me and kind of stuck out in my head was that disconnect between the messages that people get about recovery, and just the realities of the kinds of challenges that people struggle with. And then I came across this idea, this theory of recovery capital. So it's not my theory, it was developed by two other researchers, William Cloud and Robert Grandfield. But once I started reading about recovery capital, it really clicked with me because I thought this is exactly what I was observing as a practitioner. So from the get go, I was interested in doing some research related to recovery capital. And that kind of brings me I guess, to where we are today that I've had the chance to dive into that topic further and continue to do research on it. And ultimately, I'm really interested in using recovery capital to shift the lens that we use to look at addiction, especially for people that are homeless people that don't have a lot of income, people that are marginalized or otherwise lacking in resources.
Nada Fox 03:49
Thank you so much. So you've highlighted the intersection of homelessness, homelessness, excuse me, and health issues such as addiction recovery, could you delve into how stable housing plays a role in supporting individuals with substance use disorders on their path to recovery?
Dr Elizabeth Bowen 04:08
Absolutely. So I think there's first of all, I think sometimes there's a stereotype that if people are homeless and struggling with an addiction issue, that that addiction is the cause of their homelessness. And while it could be a contributing factor for some people, that's not always the case. And fundamentally, homelessness is really about a lack of affordable housing in this country. And being homeless is very traumatic for a lot of people. So often substance use is a way to cope with that for a lot of people with the trauma that comes with losing one's home and everything that goes along with that. So that's just to point out that it's often not as simple as somebody having an addiction issue and that leading to them becoming homeless. So that said, there is a lot of co-occurring between these problems between Homelessness and substance use problems with regard to all kinds of different substances. But to me, the kind of key takeaway here is just that it's so difficult to address a substance use problem without addressing the housing piece. And historically, that's kind of what we asked people to do. So housing, services and services for people experiencing homelessness, traditionally, were set up that people really had to kind of prove themselves to get into housing. So people had to first go into a shelter system, then establish sobriety worked towards various goals and kind of prove they were, quote, unquote, ready for housing. And then finally, they could be rewarded with getting access to some kind of affordable housing program. So that's like the, the history here of a lot of homeless services. And some programs still do operate that way. But there has been a paradigm shift in the past couple of decades in the United States and in other places toward this idea of housing first, and that was the kind of program that I worked for, in my social work practice experience. So Housing First is exactly what the name sounds like, it flips that idea of having to prove that you're ready for housing, and tries to get people into housing as soon as possible with the idea that once somebody has housing, then they have that foundation of stability from which you can work on other things. And often these issues are all tied up together. So it's not just addressing somebody's substance use problem, but it's also addressing other kinds of health issues that might also being doing treatment for mental health issues for underlying trauma, linking people to employment resources, or education, all these things affect one another. But it's hard to work on any of them without stable housing. So that's what the housing first model does is get people into housing more quickly, so that you can connect people with resources and start to work on their goals with regard to recovery, or however they define addiction recovery, as well as any other goals that they might have.
Nada Fox 07:04
I think it's very interesting, because it's kind of dealing with the issue in a Maslow's sort of way like we have to deal with well, you know, the very first bottom of the pyramid, their physical safety those needs stable shelter and housing in order to even think about the next steps.
Dr Elizabeth Bowen 07:19
Yeah, exactly.
Nada Fox 07:20
It's interesting that you bring up that that wasn't always the case, because we kind of put the burden on the individual for a long time then, and expected them to be able to solve all of these problems prior to addressing that most basic, basic right. So thank you so much for putting that into perspective for us. Now, you talked about housing first and working in those types of groups. And you've collaborated a lot with local service providers, like the homeless alliance of Western New York, and it's just a practical application of your research. So how do these partnerships contribute to addressing addiction and substance use disorders within this community?
Dr Elizabeth Bowen 08:02
Yeah, there's a lot of I think, really great services in Western New York, and a lot of excellent providers that are trying to do exactly that. But the whole idea with Housing First is that it's really individualized, depending on the individual persons goals. And so there's not you know, one way that programs, address addiction and help to facilitate recovery, it really depends on you know, the individual client and what they want to work toward. And that was the same way with the program that I used to work in, in my social work practice experience. So housing first programs tend to take I'm sure there's some variations, but most take a harm reduction perspective, meaning that people don't necessarily have to define their recovery as being abstinent from whatever substance they were using. When you take a harm reduction perspective, you can work with people on whatever goals they have. So sometimes that is abstinence. It certainly doesn't preclude that. But sometimes their goal might be, you know, to switch from using one substance that's particularly risky, in various ways to a substance that might be safer and might have to do with using or drinking less it might have to do with the situations in which a person uses a substance that might have to do with the effects on their health or on their life, and how can they, you know, reduce those negative effects but not necessarily commit abstinence, if that's not where they're at or what they're ready for. So that's my I think biggest thing that I've observed about various programs here, as well as just with housing first, in general, is I think, programs often do a really good job of trying to honor that and work with people to meet them where they're at and to let people define the recovery way that they wanted to find it and then connect people with resources based on their specific goals.
Nada Fox 09:59
Thank you so much. I think it's so interesting that you've kind of defined like a harm reduction approach to it, and how recovering might not necessarily be a linear thing. It ebbs and flows, and people are trying, and we're all people. And sometimes we trip and make mistakes. But that doesn't mean. So I know you're you lead this big NIH study, and you came up with the multi dimensional inventory of recovery capital. Can you tell our audience a little bit about what this is? And how does this measure specifically address the needs of diverse populations?
Dr Elizabeth Bowen 10:09
Absolutely. Yes. I would love to. So I will back up a little bit and talk about what recovery capital is first, and then tell you about this measure. So as I said earlier, when I moved from practice into becoming a researcher, I happen to come across this great article on this theory of recovery capital, and I hadn't heard of it before. But when I read it, it really resonated with me right away. So developed by a William cloud, and Robert Greenfield. And Robert Greenfield is here at UB, by the way. So that was kind of a happy accident for me, when I started at UB was that I realized, Oh, I'll get to, you know, work with the developer of recovery capital. So in any case, they had done this study, looking at people who recovered from substance use problems without formal treatment. And so that's often called natural recovery or unassisted recovery. So meaning people that don't go to inpatient or outpatient treatment, often don't even go to AAA or NA or other 12 step meetings, just people that on their own, recognize they have a substance use problem, and are able to address it and recover. And this is actually a lot more common. I don't know the specific statistics off the top of my head, but it's more common than a lot of people think so not everybody that recovers necessarily goes through formal treatment, or through 12 steps. Um, so in any case, cloud and Greenfield, recognize that and we're interested in looking at, okay, so if people are able to recover without treatment, how do they do it? Like, what are their strategies? So they did a really nice qualitative research study where they interviewed various people, I think this was in Colorado, where they both were working at the time. And so they found people that had recovered in this way, and interviewed them about like, how did you do it? What strategies to use. And then based on that, analyzing those interviews, what they found was that people talked a lot about things like their social networks. So needing to change if they hung out with a lot of friends that were drinking or using, they had to change their social network, they talked about tapping into other kinds of social support. So maybe they weren't in treatment, but they just had a good friend or family members, who understood them and supported their goals and doing that. People talked about kind of their own knowledge, learning about addiction, being able to understand it better themselves, we use that they develop their own coping strategies, people talked about hobbies and other things that they were able to tap into in their lives instead of the substance use problem. And so through analyzing all of that thought, and Grandfield, came up with this idea of recovery capital. And so what that means is, it's just a term for the different resources that people have that can support their recovery from addiction. And there's four major categories to ID. So it's social capital. So that's the social connection, social support, your social network, a human capital, those are the characteristics of a person. So like your knowledge, your education, spirituality, just things about you personal characteristics that can help in recovery, physical capital, that refers to things like housing, like we were talking about earlier. So like those tangible resources, housing, employment, transportation, income, health insurance, just those basic resources that are really critical for Foundation for Recovery. And then the last one is cultural capital. And so this has to do with feeling like you can connect to a culture that support your recovery. And sometimes that might be something like a 12 step group, or some other kind of sober recreation group, or it might also just be connecting to however you define your own culture, and finding elements within that culture that support or affirm your recovery. So that's cultural capital. So those are the four categories. So again, I just read about that as a theory and thought, that's really cool. I'd like to do some research on this. And then I kind of dove into it deeper over the years. And one thing I got interested in was, how do you measure this? So this idea of recovery capital, I think is pretty popular at this point. In a lot of people research it, it's pretty popular in practice settings to like people are, are interested in this idea. And there are different ways to measure it. So other people have already made surveys to measure recovery capital, but I took a really close look at some of them, and found there often were some issues with them. So one problem was they sometimes deviate from this theory of recovery capital. So for example, recovery, capital doesn't say anything about abstinence, you can define recovery, however you want, and still talk about recovery capital. But then when I looked closely at some of these measures, and you look at the actual items they have on them, some of them would have items that would ask that would say things about, you know, abstaining, or not using, and I thought that doesn't exactly, you know, fit with the theory. So that was one thing. And then I also looked at a diverse population. So as a social worker, and given my practice background, I know that, you know, sometimes there's a tendency to assume that something that's tested mainly with white people, mainly with middle class people, sometimes mainly with men, so lack of gender diversity, there can be this assumption to assume that like, it's going to work for everybody, when we know, that's not often the case. And so I was interested in how were these measures developed, were they tested with diverse audiences, and I found that often they weren't, often they were usually a some gender diversity, but it was often mostly white people, mostly middle class people. So I thought, we don't even know if these are really, you know, reliable and valid for more diverse audiences or populations. So that's what ultimately led me to propose this grant and was fortunate to get funding to make a new Ultra Measure recovery capital. And I think the part I got most excited about is that we really got to do it from the bottom up. So that was another thing that often researchers just come up with the items that go on these tools, and then they test it out. But it's often the researchers coming up with it. And I wanted to really involve people with lived experience. So people who are in recovery themselves or people working in the recovery field, to get their perspective on what should we actually ask on this? And how should we phrase the questions because it gets, I know, that seems like a small thing. But that becomes really important, because we know words are important. And the way that you say something, can sometimes you know, just one or can make a difference with how people interpret it. So me and my team put a lot of thought into, we did come up with some initial like starting points of like, Should we ask about this. But then we did a lot of focus groups and interviews with people in recovery, mainly people in recovery, some people working in the service system, as well. And of course, there's sometimes some overlap between those two groups. So we got really great feedback from people about what we should ask what we shouldn't ask how to ask it. And then based on that, we were able to make a draft version of this measure called the multi dimensional inventory of recovery capital, I call it the Merck or mIRC, for short. And we did other testing, so then we gave it to a much larger group of people, but still with a lot of attention to diversity. So when we did test it, we were able to do it with an audience that was economically diverse, racially diverse, gender diverse. And it's not perfect, I think no research is but we were able to get a pretty broad group of people to fill this out. I should also say diverse with regard to recovery experience. So we had people that had been through treatment. And then we also have folks that would be in that natural recovery category who had not been through treatment. So we were able to get those perspectives represented as well. So after lots of work to test this, and then make some changes and refine it, we were able to finalize the measure last spring it and make it publicly available. So it is out there now for anybody who would like to use it. It's on we have a website through the UB school social work. So if you Google UB school, social work, recovery capital or Merck mIRC, it should come up and there's a little bit background on it. And then you can download the tool there. So it's out there. And my hope is that people, both researchers, and people in practice or somebody in recovery, that might be interested in using this tool for themselves. My hope is that people will use it and find it informative.
Nada Fox 19:19
Well, it's definitely informative. I went through and kind of did it on my own, just kind of do a self assessment, you know, which I think is kind of interesting and gives you a different perspective, and, and just yourself and what you're doing now. So as an educator, you teach courses on substance use and addiction. How do you approach these subjects in your teaching? And what insights do you aim to impart on future social workers in the field of addiction?
Dr Elizabeth Bowen 19:50
Yeah, thanks for asking about that. I think the way that I teach about addiction is very much in line with the way that we've been talking about it here. So I've tried to just emphasize this, there's not one definition of recovery that people can define that in a lot of different ways I do teach about recovery capital. So I do think that it's important for social workers and other people working in the recovery field, to know about that, and to have the sense that it's not just about what's internal to someone, not just about their motivation, but really about the resources. And that's a very social work view. We talk a lot in social work about people within their environments, and I tried to really drive that home, specifically in addiction practice and with recover. So we talked about the need for housing, we talked about how would you look at other forms of recovery capital that a person either has, so we can emphasize those strengths, as well as looking at where they might be struggling a bit, and how we can address those issues. And I talk a lot about equity issues as well when I teach about addiction. So, you know, I think you can't really talk about these issues without talking about drug policy, without talking about how that has been implemented in really racist and classist ways in the United States and looking at those, addressing those core systemic issues. Because ultimately, it's, it's not enough to just treat, I think the people in front of us that clinical practice is important. But I also want any students that I interact with to come across with that systemic lens, so that we're also looking at not just helping individual people, but thinking about changing the whole system. So that's at least what I shoot for. And then I also tried to go in with an open mind myself and to learn from my students, because that is something I found that I really do. Learn from people every time I teach, even when I teach the same class over multiple years, because the students are always different. And they bring different perspectives, different lenses, I often have some students in recovery in my classes, and who sometimes aren't open, you know, don't want to be that public about it. But then sometimes I have students that are very comfortable sharing about their own recovery backgrounds. So I always learn from that. And I always try to go in with that mindset, to hear from different people and to have my own perspectives challenged and expanded by what I learned.
Nada Fox 22:18
It's interesting because you talk about overviewing it from a systemic point, kind of looking at the big picture. And this is kind of the synergy between public health and social work, right? Like we're all trying to look at things from the big picture addressing the inequities talking about it. What do we need to do? How do we change this? How do we make this more equitable? Right?
Dr Elizabeth Bowen 22:40
I think there is a lot of overlap. A lot of synergy. Yeah. With Social Work and public health, for sure. Absolutely.
Nada Fox 22:45
And I think what people that like are kind of unfamiliar with public health, like it's always easier to explain it like it's very broad, big picture, I feel. Yeah. We're not treating an individual. But these anecdotal things lead to, you know, the evidence for what's going on in our in our communities in our state or however macro we want to get. So earlier today, you talked about your, you know, trauma informed care, and that sort of stuff. And you highlighted the how you use this in your framework. So I was hoping that you could answer this question, how does your policy analysis framework is based on trauma informed care? How does this approach contribute to addressing substance use disorders within the homeless population? And what policy changes do you believe could make a significant impact going forward?
Dr Elizabeth Bowen 23:47
Yeah, that's a great question. I love thinking about policy and talking about that. Um, so to just explain about this framework. So several years ago, a colleague, Shanta Murshid, and I developed this framework for trauma informed policy analysis that was then published in the American Journal of Public Health. And what we were trying to do with that was take this idea of trauma informed care, which is something we talk about a lot in social work. And that's basically the idea that for any kind of services, so mental health treatment, addiction, treatment, housing, whatever it may be, that it's important to think about delivering those services in a way that's trauma informed meaning that recognizes a lot of people that seek services have been through different kinds of trauma, like I talked about with populations experiencing homelessness, and sometimes people can be re traumatized in the process of seeking services. So how can we try to help people feel safe and recognize what they've been through, recognize how that might be affecting whatever problems or issues they present with. And then also try to prevent retraumatization from happening while people are getting services. So that's the whole idea of trauma. informed care. And the UB School of Social Work has been a big leader in that we have some great resources on that, and on how to do that. But my colleague Shunta Murshid, and I had gotten to talking about kind of taking the next step of taking it to that more macro level. So we just had started talking about what if we weren't, you know, just trauma informed in our services, but we tried to have policy that was more trauma informed I, with the aim of really trying to prevent trauma from occurring in the first place. Because if you think about traumas that happen in so many communities, they are systemic, and get they are potentially preventable. So that's how we got to talking about how you would implement principles like safety, and choice and empowerment, those are core principles of trauma informed care. So this paper that we wrote was about what those policies are, what those principles would look like in policy. So in laws and other kinds of high level policies. And so to answer your question about what that look like for people experiencing homelessness and addiction issues, to meet the most fundamental policy change, there would be expanding access to affordable housing. And I mean, the type of housing programs I was talking about, so Housing First, specifically, but also just affordable housing in general, because while a lot of people do need, those kinds of services that come along with Housing First there are, there are many people that experience homelessness, really, just as an economic issue, they might be in some kind of short term financial crisis or something like that. And some kind of just financial assistance, rental assistance, not even necessarily a huge amount of money, but at the right time, and being able to access that in a timely way that could prevent homelessness entirely for a segment of the population. So we really need more affordable housing across the board. And one thing I always try to communicate to people is that, you know, in the United States, we've never made housing and entitlement benefit. So meaning certain programs like Medicaid, or SNAP, which is what people sometimes called food stamps, those are entitlements, meaning if people are eligible for them, and they apply, they're entitled to get it. So the government can't say, like, oh, we ran out of money for that this year, you're eligible, but we're not going to give it to you. So we don't do that for certain programs. But that's not what we've done with housing. So housing has always worked the opposite way where people can be eligible and apply. And they have to wait years, sometimes, you hear about weightless for supportive housing, or for other affordable housing, that are years long, and of course, expecting people to wait years for something as basic as housing. What are people supposed to do in the meantime, it doesn't make sense. So that, to me, would be the most, the biggest trauma informed change we can make would simply be expanding access to housing, and that would take a big investment in various kinds of affordable housing. But it is something I think that's doable. And it's a policy choice that so far in this country, we've chosen not to do it. So that is the biggest change that I can think of.
Nada Fox 28:19
Thank you so much. We'll just continue along that and I think this kind of you might have already answered this. But what changes do you hope to see in public health and the social work landscape in the future? And it seems like a housing first policy, and affordable housing, is there anything else that you would like to you would hope to see in the landscape of public health and social work in the future?
Dr Elizabeth Bowen 28:43
Yeah, good question. So in addition to expanding access to housing through an increase in funding for affordable housing, I'm over a lot I would like and help to see just programs to move toward greater accessibility. And so I just think about specifically with addiction recovery services. Currently, I think there are some barriers that don't necessarily need to be there. And that do prevent people from getting help. And by that, I mean both financial barriers, so if people want various kinds of treatment, but can't afford them, but then also things like I have a colleague that does some research on methadone maintenance treatment, and how, you know, because of current policies that people have to go to a clinic generally to get methadone if they're getting that for their recovery from an opioid problem. And it's hard to get take home doses. And then obviously, it's hugely inconvenient to people to have to go somewhere every day, or almost every day to pick up this dose of medication and take it on site. A lot of people find those processes to be dehumanizing as well. So I look at things like that. And I think about how could we be trauma informed and how could we just increase recovery capital by make Seeing all kinds of various treatments more accessible to people. And so I think of my colleague who, you know, kind of put that issue on my radar. But I think about things like that. So if methadone and other kinds of medications for addiction treatment, for example, were more accessible to people so easier to get, if you could get it, you know, in your home, I think that would increase choice that for a lot of people would increase dignity and privacy as well as just making it more accessible in a practical manner. So that's one example. But in general, that's something I think about with policy change the intersects across social work and public health. Just how can we make treatment and recovery services more accessible to more people, as well as more trauma informed?
Nada Fox 30:49
People experiencing homelessness isn't an a population that's kind of popular or the most sought after in these sorts of discussions. And it's important that we highlight this community and they're not so hidden. And yes, they're at the forefront.
Dr Elizabeth Bowen 31:06
Well, right. And I saw the you know, with your theme being about addiction, exactly. People, when people are talking about addiction and recovery issues, they're not always thinking necessarily of a really marginalized population like that, like people that don't have stable housing. So I'm happy that I can kind of bring that perspective into the conversation. Yeah.
Nada Fox 31:25
And it's, and it's nice, because I think, not on purpose, but people tend to do this. It's their fault, sort of lens on this community. And that's, that's not fair to this community. It's, you know, it's not so thank you so much for, you know, giving the audience that sort of perspective. Last question for you. It's not too horrible. What is what if you could have one thing for our listeners to walk away with from this discussion today? What would that be?
Dr Elizabeth Bowen 32:01
Good question. If I had to say one thing for listeners to walk away with from today, I guess it would be just to think about recovery holistically. And to think about both addiction and homelessness as societal problems more than personal problems. So to look at how all of the different policy choices that we make, as a society, contribute to these issues, or access to treatment and recovery resources, and I just think it's so critical to shift the thinking from looking at these problems as individual failings, to looking at them more as a byproduct of policy failures and of choices that we've made as a society. So to bring that lens and specifically to be a lot more holistic in the way that we think about addiction recovery and have conversations about it. And recovery capital has been a big part of how I think about that. And I hope that that can be a useful tool that other people will think about and learn more about too.
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